The Molecular Biology Society of Japan

4066 results (1661 - 1670)

[1P-0692(3PS18-4)] Dynamic Roles of GTP Metabolism in Cancers—Challenge for a New, Selective and Safe Approach to Eradicate Cancers

Satoshi Kofuji1, Akiyoshi Hirayama2, Koichi Okumura1, Kara Finley1, Naoya Sakamoto3, Masaru Mori2, Hirofumi Yoshino1, Akshiv Malhotra1, Mikako Warren4, Kazutaka Sumita1, Annmarie Ramkissoon4, Lionel Chow4, Tatsuya Ozawa5, Eric Holland5, Takashi Kobayashi6, Toshinari Yamasaki6, Shinsuke Shibuya7, Eijiro Nakamura6, Osamu Ogawa6, Hiroaki Wakimoto8, Craig Horbinski9, Wataru Yasui3, Tomoyoshi Soga2, 〇Atsuo T. Sasaki1 (1.UC Cancer Institute, Univ. of Cincinnati College of Medicine, USA, 2.Institute for Advanced Biosciences, Keio Univ., JAPAN, 3.Institute of Biomedical and Health Science, Hiroshima Univ., 4.Cincinnati Children's Hospital, USA, 5.Fred Hutchinson Cancer Research Center, USA, 6.Dept. of Urology, Kyoto Univ. School of Medicine, JAPAN, 7.Dept. of Diagnostic Pathology, Kyoto Univ. Hospital, 8.Dept. of Neurosurgery, MGH/Harvard Medical School, USA, 9.Northwestern Univ., USA)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[1P-0693] De novo GTP pathway is required for the proliferation of glioblastoma

〇Satoshi Kofuji1, Akiyoshi Hirayama3, Mikako Warren2, Kazutaka Sumita1, Hirofumi Yoshino1, Koichi Okumura1, Akshiv Malhotra1, Annmarie Ramkissoon2, Lionel Chow2, Hiroaki Wakimoto4, Paul Mischel5, Craig Horbinski6, Tomoyoshi Soga3, Atsuo T. Sasaki1 (1.Univ. of Cincinnati College of Medicine, USA, 2.Cincinnati Children's Hospital, USA, 3.Keio Univ., 4.MGH/Harvard Medical School, USA, 5.Univ. of California at San Diego, USA, 6.Northwestern Univ., USA)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[1P-0695] The analysis of PGAM model mice

〇Takumi Mikawa1, Ken Ito1, Itsuo Murakami1, Nobuya Inagaki1, Hiroshi Kondoh1,2 (1.Department of Diabetes, Endocrinology and Nutrition, Graduate School of Medicine, Kyoto University, 2.Geriatric unit, Kyoto University Hospital)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[1P-0697] Discovery of novel biomarkers by metabolome analysis using pre- and post-surgery serum samples and surgical tissue from hepatocellular carcinoma patients

〇Shohei Kinoshita1,2, Hiroshi Tadano3, Daisuke Kaziura3, Hisami Okumura3, Mitsuo Shimada4, Yuji Morine4, Akiyoshi Hirayama1,2, Tomoyoshi Soga1,2,5, Masaru Tomita1,2,5 (1.Inst. Adv. Bio. Sci., Keio Univ., 2.Grad. Sch. Media and Governance, 3.Tokushima Univ. Grad., Clin. Nutr. and Food Management.,, 4.Tokushima Univ. Grad., Digestive and Pediatric surgery.,, 5.Dept. Environment & Info. Studies., Keio Univ.)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[1P-0698(1PS8-7)] Glutamine synthetase function overrides a novel metabolic checkpoint of cell growth mediated by Hypoxia-Inducible Factors

〇Shojiro Kitajima1, Kian Leong Lee1, Ruby Yun-Ju Huang1, Henry Yang1, Marito Araki2, Hiroyuki Kato1, Lorenz Poellinger1,3 (1.Cancer Sci. Inst. of Singapore, Nat. Univ. of Singapore, 2.Dept. of Transfusion Med. and Stem Cell Regulation, Juntendo Univ. Grad. Sch. of Med., 3.Karolinska Institutet, Department of Cell and Molecular Biology)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[1P-0700] Prolyl hydroxylase (PHD) as a therapeutic target for metformin-associated lactic acidosis (MALA)

Tomoko Oyaizu-Toramaru1,2, Tomohiro Suhara1,2, Noriyo Hayakawa1,3, Takashi Nakamura1, Shizuka Minamishima2, Kyoji Yamaguchi4, Takako Hishiki1,3, Hiroshi Morisaki2, Makoto Suematsu1, 〇Yoji Andrew Minamishima1,2,5 (1.Dep. of Biochem., Keio Univ. Sch. of Med., 2.Dep. of Anesth., Keio Univ. Sch. of Med., 3.Translational Res. CTR., Keio Univ. Sch. of Med., 4.Rare Dis. & LCM lab., Daichi Sankyo Co. Ltd., 5.Med. Inst. Bioreg., Kyushu Univ.)

The 39th Annual Meeting of the Molecular Biology Society of Japan

4066 results (1661 - 1670)