[2P-0578] Alteration of oligomeric states and subcellular localization of ALS2 mutants underlie the pathogenesis of ALS2-linked motor neuron diseases

〇Kai Sato¹, Kyoko Suzuki-Utsunomiya¹, Yui Hiratsuka¹, Shun Mitsui¹, Suzuka Ono¹, Asako Otomo¹, Shinji Hadano¹ (1.Dept Mol Life Sci,Tokai Univ Sch of Med)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[2P-0579] Role of MTCL1, a microtubule crosslinking and stabilizing protein, in the formation of axon initial segment

〇Tomoko Satake¹, Atsushi Suzuki¹ (1.Dept. of Med. Life Sci., Grad. Sch. of Med. Life. Sci., Yokohama City Univ.)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[2P-0580] Increasing c-fos expression through MAPK/CREB pathway precedes site-specific neuronal degeneration in methylmercury-intoxicated model mice

〇Masatake Fujimura¹, Fusako Usuki² (1.Dept. of Basic Med Sci., Nat. Inst. for Minamata Dis., 2.Dept. of Clin. Med., Nat. Inst. for Minamata Dis.)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[2P-0581] Proteasome Activator PA28 gamma regulate neuronal function of cerebellar Purkinje cells

〇Kazukiyo Nakamura¹, Taichi Amagasa¹, Naoto Tsuruoka¹, Hirotake Kasai², Kohji Moriishi², Takae Hirasawa¹ (1.Grad. Shc. Biosci. Teikyo Univ., 2.Dept.Microbiology, Fac.Med., Univ. Yamanash)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[2P-0582] The role of the Atg5/Atg7-independent autophagy in the brain

〇Nobuhiro Fujikake¹, Hirofumi Yamaguchi¹, Satoko Arakawa¹, Shigeomi Shimizu¹ (1.Dept. of Pathol. Cell Biol., Med. Res. Inst., Tokyo Med. Dent. Univ.)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[2P-0583] New insights into the chromosomal integrity in microglia associated with autophagy defect

〇Sarasa Yano¹, Fuminori Tsuruta², Ban Sato², Tomoki Chiba² (1.The Coll. of Biol. Sci., Sch. of Life and Environ. Sci. Univ. of Tsukuba, 2.Grand. Sch. of Life and Environ. Sci., Univ. of Tsukuba)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[2P-0584] A new insight into the effect of cold shock protein on autophagy in brain

〇Takuma Aihara¹, Fuminori Tsuruta¹, Ban Sato¹, Tomoki Chiba¹ (1.Grad. Sch. of Life and Environ. Sci., Univ. of Tsukuba)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[2P-0585] Identification of chromosomal regions interacting with susceptibility loci for Alzheimer's diseases

〇Masataka Kikuchi¹, Norikazu Hara², Mai Hasegawa³, Akinori Miyashita², Ryozo Kuwano^2,4, Takeshi Ikeuchi², Akihiro Nakaya¹ (1.Dept. of Genome Inform., Grad. Sch. of Med., Osaka Univ., 2.Dept. of Mol. Genet., Brain Res. Inst., Niigata Univ., 3.Div. of Mol. Biol., RIBS, Tokyo Univ. of Sci., 4.Asahigawaso Res. Inst.)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[2P-0586] The effects of Azuki extracts on anti-Alzheimer's disease

〇Honami Miyazaki¹, Minami Watanabe², Yoko Okamoto³, Shinichi Yonekura^1,2,3 (1.Interdisciplinary. Grad. Sch. of Sci. and. Technol., Univ. of Shinshu, 2.Fac. of Agr., Univ. of Shinshu, 3.Inst. for Biomed. Sci., Univ. of Shinshu)

The 39th Annual Meeting of the Molecular Biology Society of Japan

[2P-0587] Role of 8-oxoguanine accumulated in nuclear or mitochondrial DNA in the development of Alzheimer’s disease

〇Sugako Oka^1,2, Zijing Sheng¹, Julio Leon¹, Daisuke Tsuchimoto¹, Kunihiko Sakumi¹, Yusaku Nakabeppu¹ (1.Div. of Neurofunc. Genomics, Med. Inst. of Bioreg., Kyushu Univ., 2.Inst. of Life Science, Kurume Univ.)

The 39th Annual Meeting of the Molecular Biology Society of Japan