[2P-355] Differential gene regulation by a synthetic vitamin D receptor ligand and active vitamin D in human cells

^〇Yoshiaki Kanemoto^1,2, Miho Iwaki³, Takahiro Sawada^1,2, Koki Nojiri^1,2, Tomohiro Kurokawa^2,4, Rino Tsutsumi³, Kazuo Nagasawa³, Shigeaki Kato^1,2,4 (1.Graduate School of Life Science and Technology, Iryo Sosei University, 2.Research Institute of Innovative Medicine, Tokiwa Foundation, 3.Graduate School of Technology, Tokyo University of Agriculture and Technology, 4.School of Medicine, Fukushima Medical University)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-356] Nanoscopic elucidation of binding dynamics of estrogen receptor α (ERα) to estrogen response element (ERE) in the presence or absence of estrogen

^〇Goro Nishide¹, Tomoka Ishibashi², Keesiang Lim³, Masaharu Hazawa⁴, Yuka Inaba⁵, Hiroshi Inoue⁵, Ayami Matsushima², Richard Wong^3,4 (1.Division of Nano Life Science in the Graduate School of Frontier Science Initiative, WISE Program for Nano-Precision Medicine, Science, and Technology Kanazawa University, 2.Department of Chemistry, Faculty of Science, Kyushu University, 3.WPI-Nano Life Science Institute, Kanazawa University, 4.Cell-Bionomics Research Unit, Institute for Frontier Science Initiative, Kanazawa University, 5.Metabolism and Nutrition Research Unit, Institute for Frontier Science Initiative, Kanazawa University)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-357] Repression of AR function by androgen receptor splicing variant (AR-V7).

^〇Takahiro Sawada^1,2, Yoshiaki Kanemoto^1,2, Tomohiro Kurokawa^1,2,3,4, Koki Nojiri^1,2, Shigeaki Kato^1,2,3 (1.Health Sciences Research Center, Iryo Sosei University, 2.Research Institute of Innovative Medicine, Tokiwa Foundation, 3.School of Medicine, Fukushima Medical University, 4.Joban Hospital, Tokiwa Foundation)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-358] Cannabidiolic acid induces expression of PPARbeta/delta target genes in human breast cancer MDA-MB-231 cells

Masayo Hirao-Suzuki¹, Koki Kanameda², Takayuki Koga³, Masufumi Takiguchi¹, Narumi Sugihara², ^〇Shuso Takeda² (1.Faculty of Pharmaceutical Sciences, Hiroshima International University, 2.Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, 3.Department of Pharmaceutical Sciences, Daiichi University of Pharmacy.)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-359] PP2A inhibitor SET promotes mTORC1 and Bmi-1 signaling through Akt activation and maintains the colony-formation ability of cancer cells

^〇Naoki Kohyanagi¹, Nao Kitamura¹, Shunta Ikeda¹, Shusaku Shibutani², Koichi Sato¹, Takashi Ohama¹ (1.Laboratory of Veterinary Pharmacology, Yamaguchi University Joint Graduate School of Veterinary Medicine, 2.Laboratory of Veterinary Hygiene, Yamaguchi University Joint Graduate School of Veterinary Medicine)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-360] Regulation of activity of protein phosphatase PPM1K by phosphorylation

^〇Yuka Goda¹, Jin Osawa^1,2, Noriyuki Sueyoshi¹ (1.Kagawa University, Graduate School of Agriculture, 2.Ehime University, Graduate School of Agronomy)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-361] Exploration of phosphorylation sites and regulatory mechanism of protein phosphatase PPM1L

^〇Chika Usuki¹, So Inoue¹, Jin Osawa^1,2, Noriyuki Sueyoshi¹ (1.Kagawa University, Graduate School of Agriculture, 2.Ehime University, United Graduate School of Agricultural Sciences)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-362] Biochemical and histological characterization of mouse calcium/calmodulin-dependent protein kinase kinase β/2 splice variants lacking exon 16

^〇Satomi Ohtsuka¹, Yumi Miyai², Hiroyuki Mima¹, Masaki Magari¹, Yoichi Chiba², Futoshi Suizu³, Hiroyuki Sakagami⁴, Masaki Ueno², Hiroshi Tokumitsu¹ (1.Applied Cell Biology, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, 2.Department of Pathology and Host Defense, Faculty of Medicine, Kagawa University, 3.Oncology Pathology, Department of Pathology and Host-Defense, Faculty of Medicine, Kagawa University, 4.Department of Anatomy, Kitasato University School of Medicine)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-363] Identification and application of active ingredients that act on PKC and DGK to inhibit wrinkle formation

^〇Ayaka Inoue¹, Koji Takaoka², Kanako Kondo¹, Syuji Ueda¹, Itsuko Fukuda¹, Yasuhito Shirai¹ (1.Dept. of Appl. Chem. In Biosci., Grad. Sch. Of Agri. Sci, Kobe Univ. , 2.DSR Co., Ltd)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-364] Comparison among MARK/Per1 family members revealed that MARK4 promotes tau accumulation via a specific mechanism

^〇Iori Kato¹, Grigorii Sultanakhmetov¹, Akiko AsaDa^1,2, Taro Sato^1,2, Kanae Ando^1,2 (1.Tokyo Metropolitan University, Graduate School of Science, Department of Biological Sciences , 2.Tokyo Metropolitan University, Faculty of Science, Department of Biological Sciences)

The 96th Annual Meeting of the Japanese Biochemical Society