[A01-2am] 16. Natural Products Chemistry, Chemical Biology

[A01-2am-16] Design, synthesis, and biological evaluation of α-helix mimetics having skeletally diverse macrocyclic mid-sized scaffolds

^○Takahiro Shimizu¹, Norihito Takahashi¹, Vincent Huber², Yasunobu Asawa³, Hiroki Ueda³, Atsushi Yoshimori⁴, Yukiko Muramatsu⁵, Hiroyuki Seimiya⁵, Hiroyuki Nakamura³, Hiroyuki Kouji², Hiroki Oguri⁶ (1. Tokyo University of Agriculture and Technology, 2. Oita University Institute of Advanced Medicine, Inc., 3. Tokyo Institute of Technology, 4. Institute for Theoretical Medicine, Inc., 5. Japanese Foundation for Cancer Research, 6. The University of Tokyo)

[Lang.] Japanese

Keywords:α-Helix Mimetics, Macrocycles, Olefin Metathesis, Hypoxia Induced Factor 1α, Skeletal Diversification