[A24-3am] 17. Biofunctional Chemistry, Biotechnology

[A24-3am-05] NASA-type irreversible inhibitor for HDM2-p53 protein-protein interaction (1): Evaluation of structure-activity relationship using recombinant HDM2

^○Masaharu Kawano¹, Tsuyoshi Ueda¹, Tomonori Tamura¹, Keiya Shiono¹, Fruzsina Hobor², Andrew Wilson², Itaru Hamachi¹ (1. Kyoto University, 2. University of Leeds)

[Lang.] Japanese

Keywords:Irreversible inhibitor, NASA, Covalent inhibitor