[A24-3am] 17. Biofunctional Chemistry, Biotechnology

[A24-3am-06] NASA-type irreversible inhibitor for HDM2-p53 protein-protein interaction (2): Evaluation of reactivity for intracellular HDM2

^○Tomonori Tamura¹, Tsuyoshi Ueda¹, Masaharu Kawano¹, Keiya Shiono¹, Fruzsina Hobor², Andrew Wilson², Itaru Hamachi¹ (1. Kyoto University, 2. University of Leeds)

[Lang.] Japanese

Keywords:Irreversible inhibitor, NASA, Covalent inhibitor