[1B09] Lamin B1-dependent transient nuclear softening during the zygotic transcriptional burst of mouse early embryogenesis

*Masahito TANAKA¹, Rin SAKANOUE², Atsushi TAKASU², Yasuki MIYAGAWA³, Naoko WATANABE¹, Kei MIYAMOTO³, Yuta SHIMAMOTO^1,4 (1. Laboratory of Physics and Cell Biology, National Institute of Genetics, 2. Graduate School of Biology-Oriented Science and Technology, Kindai University, 3. Laboratory of Animal Reproductive Physiology, Department of Animal and Marine Biosciences, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, 4. Department of Genetics, Sokendai University)

Time Adjustment

[1B10] Somatic epigenetic mosaicism of FDFT1 and clonal expansion of the FDFT1 epigenetically silenced cells underlies non-hereditary localized form of porokeratosis

*Akiharu Kubo^1,2, Sonoko Saito², Yuki Saito², Hisato Suzuki², Showbu Sato², Satomi Aoki², Masukazu Inoie⁴, Kenichiro Hata³, Keisuke Kataoka², Kenjiro Kosaki², Masayuki Amagai², Kazuhiko Nakabayashi³ (1. Kobe University, 2. Keio University School of Medicine, 3. National Center for Child Health and Development, 4. Japan Tissue Engineering Co., Ltd.)

[1B11] p53 secures the normal behavior of H3.1 histone in the nucleus by regulating nuclear phosphatidic acid and EZH2 during the G1/S phase

*Tsukasa Oikawa¹, Junya Hasegawa², Haruka Handa¹, Naomi Ohnishi³, Yasuhito Onodera⁴, Ari Hashimoto¹, Junko Sasaki², Takehiko Sasaki², Koji Ueda³, Hisataka Sabe⁵ (1. Hokkaido Univ., Graduate School of Medicine, Department of Molecular Biology, 2. Tokyo Medical and Dental Univ., Medical Research Institute, Department of Biochemical Pathophysiology/Lipid Biology, 3. Japanese Foundation for Cancer Research, Cancer Precision Medicine Center, Cancer Proteomics Group, 4. Hokkaido Univ., Graduate School of Medicine, Global Center for Biomedical Science and Engineering, 5. Hokkaido Univ., Institute for Genetic Medicine)

[1B12] Chromokinesin prevents early separation of chromosome arms in metaphase

*Kenji Iemura¹, Kinue Kuniyasu¹, Kozo Tanaka¹ (1. Institute of Development, Aging and Cancer, Tohoku University)

[1B13] Molecular Mechanisms of Intracellular pH-Dependent Reversible Neural Cell Migration Changes

*Katsutoshi Mizuno^1,4, Ryota Kato², Wakana Terao³, Takafumi Itoh³, Satoshi Fujita², Masami Yamada^1,4 (1. Univ. of Fukui, Dept. of Med., 2. Univ. of Fukui, Dept. of Engr., 3. Fukui Prefectual Univ., Dept of Biosci. and Biotech., 4. Univ. of Fukui, Center for Life Sci. Innov.)

[1B14] Cellular-level left-right asymmetry, cell chirality, induces the chiral collective rotation of multicellular colony

*Tomoki Ishibashi¹, Shibata Tatsuo¹ (1. RIKEN BDR)

[1B15] ERK-mediated ZO1 transition to cell-ECM adhesion structure exerts traction force to promote cell migration and invasion

*Sayuki Hirano¹, Yohei Kondo¹, Naoto Ueno^2,3, Kazuhiro Aoki^1,3 (1. Kyoto Univ., Grad. Sch. of Biost., 2. Natl. Insts. of Nat. Scis. (NINS), Int. Res. Collab. Ctr. (IRCC), 3. Natl. Insts. of Nat. Scis. (NINS), Natl. Inst. for Bas. Biol. (NIBB))

[1B16] Solo regulates the localization and activity of PDZ-RhoGEF to remodel the actin cytoskeleton in response to substrate stiffness

*Aoi Kunitomi¹, Shuhei Chiba¹, Nahoko Higashitani², Atsushi Higashitani², Kensaku Mizuno¹, Kazumasa Ohashi¹ (1. Mol. Cell. Biol., Grad. Sch. of Life Sci., Tohoku Univ., 2. Mol. Genet. and Physiol., Grad. Sch. of Life Sci., Tohoku Univ.)

[1B17] The uptake and cytosolic transfer of Rac1 via extracellular vesicles for the promotion of cell migration

*Toshifumi Fujioka¹, Tamako Nishimura¹, Shiro Suetsugu¹ (1. Nara Institute of Science and Technology. Division of Biological Science)

[1B18] Analysis of MTCL1 action on damaged microtubules

*Kentaro Ito¹, Atsushi Suzuki¹ (1. Graduate School of Medical Life Science, Yokohama City University )

[1B19] ‘Go’ and ‘Whoa’ Signals in Cell Motility: Non-catalytic role of PI3-kinase through a novel p85β/AP2-mediated endocytosis

*Hideaki T. Matsubayashi¹, Jack Mountain², Nozomi Takahashi¹, Abhijit Deb Roy², Tony Yao², Amy F. Peterson², Cristian Saez Gonzalez², Ibuki Kawamata^3,4,5, Takanari Inoue² (1. Tohoku University, FRIS, 2. Johns Hopkins University, Department of Cell Biology, 3. Tohoku University, Department of Robotics, 4. Ochanomizu University, Natural Science Division, 5. Kyoto University, Division of Physics and Astronomy)

[1B20] Deformation of the embryo affects the direction of cell migration during anterior-posterior axis formation in mouse

*Seiya Mikoshiba^1,2, Toshihiko Fujimori^1,3 (1. Division of Embryology, NIBB, 2. Graduate School of Science, Nagoya University, 3. Department of Basic Biology, School of Life Science, SOKENDAI)

[1B21] Activation of the mechanogated ion channel TRPV4 by contractile forces controls focal adhesion dynamics in migrating cells

*Karan Ishii¹, Sergey Plotnikov¹ (1. University of Toronto, Department of Cell and Systems Biology)

Session information

[1O-Ba] Oral Session 2