Symposium

[3S-Bm] Homeostasis in Living Organisms and Its Dysregulation: Unraveling Life Processes and Diseases through Biological Signals

Fri. Jul 19, 2024 9:00 AM - 11:30 AM Venue B (1F Conference Room 102)

Organizers:Ari Hashimoto(Hokkaido University), Chitose Oneyama(Aichi Cancer Center Hospital)

In the diverse cells that compose the living body, intricate signaling processes occurs both inside and outside the cell to adapt to environmental changes and maintain homeostasis. Dysregulation of these mechanisms leads to the development and progression of various diseases. In this symposium, researchers from different fields will discuss the diversity and similarity in the mechanisms that maintain homeostasis in organisms, and the relationship between their disruption and diseases.

+Add all to schedule

Opening Remarks

[3B02] A mechanism for selective loading of microRNAs into extracellular vesicles in cancer cells

*Chitose Oneyama^1,2,3 (1. Division of Cancer Cell Regulation, Aichi Cancer Center Research Institute, 2. Graduate School of Pharmaceutical Sciences, Nagoya City University, 3. Graduate School of Medicine, Nagoya University)

[3B03] Cluster formation induced by activation of the coagulation system promotes multicellular cancer metastasis

Makoto Miyazaki¹, *Hideki Yamaguchi¹ (1. Department of Cancer Cell Research, Sasaki Institute, Sasaki Foundation)

[3B04] Ciliopathies as cholesterol insufficient disorders

*Tatsuo Miyamoto^1,2, Takeshi Itabashi^1,2, Moe Hirosawa^1,2 (1. Graduate School of Medicine, Yamaguchi University, 2. Research Institute for Cell Design Medical Science)

[3B05] Molecular mechanism of immunosuppressive tumor microenvironment formation by the ARF6-AMAP1 pathway in malignant pancreatic cancer

*Ari Hashimoto¹, Haruka Handa¹, Daisuke Okuzaki², Tsukasa Oikawa¹, Soichiro Hata¹, Yoshizuki Fumoto¹, Akio Tsutaho³, Yoshihiro Nishikawa⁴, Yuzo Kodama^4,5, Satoshi Hirano³, Shigeru Hashimoto^1,6, Hisataka Sabe^1,6 (1. Department of Molecular Biology, Graduate School of Medicine, Hokkaido University, 2. Laboratory of Human Immunology (Single Cell Genomics), WPI Immunology Frontier Research Center, Osaka University, 3. Department of Gastroenterological Surgery II, Graduate School of Medicine, Hokkaido University, 4. Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, 5. Department of Gastroenterology, Kobe University Graduate School of Medicine, 6. Institute for Genetic Medicine, Hokkaido University)

[3B06] Organ-crosstalk mechanisms in chronic liver disease with complications: The multifunctionality of extracellular signals

*Akiko Eguchi¹ (1. Mie University Hospital, Biobank Center (Gastroenterology))

[3B07] Genetic analysis of the “aging-signaling network”
originating from the gut

*Koki Yamada¹, Mayumi Akuta², Yuri Hirai¹, Qianmei Wu³, Akihito Harada³, Kiichiro Taniguchi², Tatsushi Igaki^1,2 (1. Kyoto Univ., Graduate School of Pharmaceutical Sciences, Department of Multicellular Systems, 2. Kyoto Univ., Graduate School of Biostudies, Department of Systems Functional Sciences, 3. Kyushu Univ. Medical Institute of Bioregulation, Transcriptomics)

[3B08] Significance of fibroblast heterogeneity and states in cancer progression and therapeutic response

*Atsushi Enomoto¹ (1. Nagoya University Graduate School of Medicine)

Closing Remarks