Symposium

[3S-Ba] [JST-CREST] Molecular cell biology of maternal-fetal interphase

Fri. Jul 19, 2024 3:00 PM - 5:30 PM Venue B (1F Conference Room 102)

Organizers:Fumiko Toyoshima(Kyoto University), Kenichi Miharada(Kumamoto University)

Mammals have a survival strategy that allows their offspring to develop adequately within the mother's body. This mammalian viviparity has an evolutionary advantage, providing a stable supply of nutrients and gas exchange from the mother to the foetus. Previous studies of mammalian embryonic development have focused on the autonomous mechanisms of the foetus. In recent years, however, the field of embryonic development has expanded to focus on the crosstalk between the fetus and the mother. In addition, the relevance of maternal environmental factors to fetal development has been highlighted. In this symposium we would like to discuss the new basic principles of mammalian embryonic development from the point of view of maternal-fetal crosstalk and their application to medical care.

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Opening Remarks

[3B11] Maternal organ remodeling and fetal development

*Fumiko Toyoshima¹ (1. Lime, Kyoto Univ/MRI, TMDU )

[3B12] Maternal-fetal interaction via membrane-associated sex steroid hormone receptors

*Ikuo Kimura¹ (1. Kyoto Univ. Department of Biostudies)

[3B13] Impact of maternal DHA-PL synthesis on maternal–fetal DHA supply

*Keisuke Yanagida¹, Ayumi Kanatani¹, Daisuke Hishikawa^2,1, Katsuyuki Nagata^1,3, Fumie Hamano³, Kenta Nakano¹, Tadashi Okamura¹, Takao Shimizu^4,1, Hideo Shindou^1,3, Takeshi Nagamatsu⁵ (1. National Center for Global Health and Medicine, 2. Nippon Medical School, 3. The University of Tokyo, Graduate School of Medicine, 4. Institute of Microbial Chemistry, 5. International University of Health and Welfare)

[3B14] Maternal sterol 27-hydroxylase is crucial for securing fetal development

*Kenichi Miharada^1,2 (1. International Research Center for Medical Sciences, Kumamoto University, 2. Lund Stem Cell Center, Lund University, Sweden)

[3B15] Breath biopsy technology targeting for ferroptosis-related volatile compounds

*Yuki Sugiura¹ (1. Center for Cancer Immunotherapy and Immunobiology, Graduate School of Medicine, Kyoto University)

[3B16] The regulatory roles of placentokines in maternal behavior

*Joji Kusuyama¹ (1. Department of Biosignals and Inheritance, Graduate School of Medical and Dental Sciences,Tokyo Medical and Dental University (TMDU))

Closing Remarks