Temporal regulation of G2 phase by ATR inhibition avoids therapy-induced senescence transition and induces cell death through sever chromosome bridges

Makoto Iimori

[3P12] Temporal regulation of G2 phase by ATR inhibition avoids therapy-induced senescence transition and induces cell death through sever chromosome bridges

*Makoto Iimori¹, Kentaro Nonaka², Hiroyuki Kitao¹ (1. Fukuoka Dental Col., Oral Medicine Research Center, 2. Kyushu Univ., Department of Surgery and Science)

Keywords:DNA replication stress, Cellular senescence, Chromosome bridge, G2 phase

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Presentation information

[3P-1] Cell growth, Cell differentiation, Cell death 3

[3P12] Temporal regulation of G2 phase by ATR inhibition avoids therapy-induced senescence transition and induces cell death through sever chromosome bridges

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