[3Ba] Physiologically active compounds

[3Ba-03] Search of the life-style related diseases prevention ingredient in Celery seeds

*Akiyoshi Sawabe^1,2, Ririka Tokuno², Tomo Ogura², Ryuji Takeda³ (1. Graduate School of Agriculture, Kindai University, 2. Faculty of Agriculture, Kindai University, 3. Faculty of Health and Welfare, Kansai University of Welfare Sciences)

Keywords:Celery seeds, life-style related diseases prevention ingredient, AGEs generation inhibitory activity test, ACE inhibitory activity test

[Objectives] In this study, we focused on life-style related diseases prevention, and examined the AGEs generation inhibitory activity and ACE inhibitory activity of the constituent included in Celery seeds for preventing aging progression and disease.
[Results] Eight compounds were isolated from Celery seeds, and their structures were established on basis of MS and NMR spectroscopy. As a result, several compounds and extracts showed remarkable activity. As for compounds and extracts, it might be used in general as supplement and food additives to take every day.