[2P-289] ZIC5 Enhances Drug Resistance of Prostate Cancer and Colorectal Cancer by PDGFD-Mediated Activation of FAK and STAT3

^○Inagaki Shota¹, Kato Chiaki¹, Shimozawa Makoto¹, Satow Reiko^1,2, Fukami Kiyoko^1,2 (1.Lab. of Genome and Biosignals, Tokyo Univ. of Pharm. and Life Sci., 2.AMED-CREST, AMED)

The 91th Annual Meeting of JBS

[2P-290] Quercetin and caffeic acid regulate senescence marker genes in human lung fibroblasts

^○Okada Yoshinori¹, Okada Mizue² (1.Laboratory on Ageing & Health Management, Graduate School of Nursing & Health, Aichi Prefectural University, 2.Nutrition Section, Ageing and Nutrition Research, Yms Laboratory)

The 91th Annual Meeting of JBS

[2P-291] Protective effect of Ecklonia cava polyphenol on ethanol-induced hepatotoxicity and its mechanism

Sawada Takuya, Goto Mayu, Yamashita Haruka, Kitano Atsuko, Yuasa Isao, ^○Kojima-Yuasa Akiko (Graduate School of Human Life Science, Osaka City University)

The 91th Annual Meeting of JBS

[2P-292(2T14a-01)] Analysis of diabetic nephropathy on podocyte-specific Bmp4 knockout mouse

^○Kangawa Yumi¹, Tominaga Tatsuya², Fujita Yui², Nagai Kojiro², Abe Hideharu², Doi Toshio³ (1.Tokushima University Graduate School of Health Sciences, 2.Tokushima University Graduate School of Biomedical Sciences, 3.Research Institute for Production Development)

The 91th Annual Meeting of JBS

[2P-293] Telomere dysfunction induces Sirtuin repression that drives liver fibrosis.

^○Amano Hisayuki, Ueda Takeshi, Ota Kazunari, Komuro Akiyoshi, Okada Hitoshi (Department of Biochemistry, Kindai university, Faculty of Medicine)

The 91th Annual Meeting of JBS

[2P-294] Study of pathophysiological importance of cholesterol transporter Niemann-Pick C1-Like 1 in the liver by using adenovirus-mediated gene delivery in mice

^○Toyoda Yu, Takada Tappei, Tomura Fumiya, Yamanashi Yoshihide, Suzuki Hiroshi (Department of Pharmacy, the University of Tokyo Hospital)

The 91th Annual Meeting of JBS

[2P-295] Age-related decrease of mitochondrial hsp70 expression in rat liver

^○Takahashi Ryoya, Odera Keiko, Kamita Masahiro (Department of Biochemistry, Faculty of Pharmaceutical Sciences, Toho University)

The 91th Annual Meeting of JBS

[2P-296] Galectin-1 is involved in the development of diabetic nephropathy

^○Kikuchi Shoya¹, Yoshida Yuto¹, Koda Koyo¹, Sango Kazunori², Yamamoto Toshiharu³, Kadoya Toshihiko¹ (1.Biotechnology, Graduate School of Engineering, Maebashi Institute of Technology, 2.Diabetic Neuropathy Project, Department of Sensory and Motor Systems, Tokyo Metropolitan Institute of Medical Science, 3.Brain Functions and Neuroscience Division, Department of Oral Science, Graduate School of Dentistry, Kanagawa Dental University)

The 91th Annual Meeting of JBS

[2P-297] Effect of LL-37, a human antimicrobial peptide, on autophagy and cell death of endothelial cells

^○Suzuki Kaori, Ohkuma Mari, Nagaoka Isao (Dept. Host Defense and Biochemical Research, Juntendo Univ. Sch. Med.)

The 91th Annual Meeting of JBS

[2P-298(2T14a-02)] Comprehensive single-cell transcriptome analysis of aging-related genes in rat hepatocytes.

^○Doshida Yuta^1,4, Funakoshi Tomoko¹, Hashimoto Shinichi², Iwabuchi Sadahiro², Lee Jaewon³, Aigaki Toshiro⁴, Ishigami Akihito¹ (1.Tokyo Metropolitan Institute of Gerontology, 2.Kanazawa University, 3.College of Pharmacy, Pusan National University, 4.Tokyo Metropolitan University)

The 91th Annual Meeting of JBS