[2P-199] v-Src causes mitotic slippage through phosphorylation of Cdk1

Horiuchi Maria¹, Kuga Takahisa¹, Saito Youhei¹, Nagano Maiko², Adachi Jun², Tomonaga Takeshi², Yamaguchi Naoto³, ^○Nakayama Yuji¹ (1.Dept. of Biochem. and Mol. Biol., Kyoto Pharm. Univ., 2.Lab. of Proteome Res., Natl. Inst. of Biomed. Innov., Health and Nutr., 3.Lab. of Mol. Cell Biol., Grad. Sch. of Pharm. Sci., Chiba Univ.)

The 91th Annual Meeting of JBS

[2P-200] A novel mechanism of inhibition of CaM kinase phosphatase (CaMKP): Specific carbonylation of CaMKP by pyrogallol derivatives

^○Ishikawa Shun¹, Obatake Rika¹, Ozaki Hana¹, Shimoda Nao¹, Nehira Tatsuo¹, Yamazaki Takeshi¹, Kinumi Tomoya², Kameshita Isamu³, Sueyoshi Noriyuki³, Shigeri Yasushi^4,5, Ishida Atsuhiko¹ (1.Grad. Sch. Integr. Arts Sci., Hiroshima Univ., 2.NIMIJ, AIST,, 3.Dept. Appl. Biol. Sci., Fac. Agr., Kagawa Univ., 4.Health Res. Inst., AIST, 5.Dept. Chem., Wakayama Med. Univ.)

The 91th Annual Meeting of JBS

[2P-201] Investigation of physiological significance of LRRK2-mediated phosphorylation of p53

^○Imai Motoki, Kawakami Fumitaka, Isaka Yuuki, Ishikawa Yuta, Yamashita Mayuka, Kawashima Rei, Maekawa Tatsunori, Ichikawa Takafumi (Departoment of Regulation Biochemistry, Graduate School of Medical Science, Kitasato University)

The 91th Annual Meeting of JBS

[2P-202] FGF1/CPP-C chimera protein protects adverse effects of C-ion radiotherapy for pancreatic carcinoma.

^○Nakayama Fumiaki¹, Kawano Mitsuko¹, Miura Taichi¹, Fujita Mayumi¹, Koike Sachiko¹, Imadome Kaori¹, Ishikawa Astuko¹, Yasuda Takeshi¹, Imamura Toru^1,2, Imai Takashi¹ (1.National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, 2.School of Bioscience and Biotechnology, Tokyo University of Technology)

The 91th Annual Meeting of JBS

[2P-203(2T12e-07)] Regulation of the osteoclastogenesis by targeting RANK-TRAF6 signaling pathway.

^○Anzai Masataka¹, Takahashi Miho¹, Nakamura Yumi¹, Kawabata Hiroshi¹, Taguchi Yu², Inoue Junichiro², Nishikawa Kiyotaka¹ (1.Doshisha University Graduated School of Life and Medical sciences, 2.The Institute of Medical Science, The University of Tokyo)

The 91th Annual Meeting of JBS

[2P-204] DA-Raf, a dominant-negative antagonist of the Ras-ERK pathway, is essential for skeletal muscle cell differentiation and apoptosis

Takahashi Kazuya, Takano Kazunori, ^○Endo Takeshi (Department of Biology, Graduate School of Science, Chiba University)

The 91th Annual Meeting of JBS

[2P-205(2T12e-09)] Novel FGF4 signal regulation mechanism by O-GlcNAc in mouse embryonic stem cells

^○Miura Taichi^1,2, Nakayama Fumiaki², Nishihara Shoko¹ (1.Department of Bioinformatics, Graduate School of Engineering, Soka University, 2.National Institutes for Quantum and Radiological Science and Technology)

The 91th Annual Meeting of JBS

[2P-206] Novel potent analogs of ACA-28, an ERK-dependent apoptosis inducer and the inhibition of cancer cell growth

^○Hamada Naoya¹, Kawasaki Aki¹, Satoh Ryosuke¹, Takasaki Teruaki¹, Tanabe Genzoh², isikawa humihiro², Sugiura Reiko¹ (1.Lab.of Mol.Pharmacogenom.,Fac.of Pharm.,Kindai Univ., 2.Pharmaceut.Org.Chem.,Fac.of Pharm.,Kindai Univ.)

The 91th Annual Meeting of JBS

[2P-207] Metabolic regulation of the CCN3 gene by glycolysis in chondrocytes

^○Akashi Sho^1,2, Nishida Takashi¹, El-Seoudi Abdellarif¹, Takigawa Masaharu³, Iida Seiji², Kubota Satoshi^1,3 (1.Department of Biochemistry and Molecular Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2.Department of Oral and Maxillofacial Reconstructive Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 3.Advanced Research Center for Oral and Craniofacial Sciences, Okayama University Dental School)

The 91th Annual Meeting of JBS

[2P-208] Molecular mechanism responsible for the decrease of protein C inhibitor expression in HepG2 cells induced by hepatocyte growth factor

^○Akita Nobuyuki¹, Okamoto Takayuki², Nishioka Junji³, Suzuki Koji⁴, Hayashi Tatsuya⁵ (1.Dept. Clin. Eng., Suzuka Univ., Mie, Japan, 2.Dept. Pha., Shimane Univ., Shimane, Japan, 3.Dept. Clin. Nutr., Suzuka Univ. Med. Sci., Mie, Japan, 4.Dept. Pha. Sci., Suzuka Univ. Med. Sci., Mie, Japan, 5.Dept. Biochem., Mie Prefe. Col. Nur., Mie, Japan)

The 91th Annual Meeting of JBS