The Japanese Biochemical Society

[1P-114] Construction and functional analysis of recombinant convulxin, platelet-aggregating snake venom through GPVI

Sasaki Tomoyuki1, Shirai Toshiaki2, Tsukiji Nagaharu2, Otake Shimon2, Tamura Shogo3, Osada Makoto4, Satoh Kaneo5, Ozaki Yukio6, Inoue Katsue1,2 (1.Dept. of Clinical Lab., Univ. of Yamanashi Hospital, 2.Dept. of Clinical and Lab. Med., Fac. of Med., Univ. of Yamanashi, 3.Dept. of Pathphysiological Lab. Sci., Grad. Sch. of Med., Nagoya Univ., 4.Sch. of Med. Tech., Gumma Paz Univ., 5.Clinical Trial Management Office of Yamanashi Hospital, 6.Fuefuki Central Hospital)

The 91th Annual Meeting of JBS

[1P-115] Identification of ubiquinone binding site of Ndi1, a yeast Type II NADH dehydrogenase, by revealing co-crystal structure with novel competitive and mixed-type inhibitors

Yamashita Tetsuo1, Inaoka Daniel K.2,3, Shiba Tomoo4, Oohashi Takumi2, Iwata So5,6,7,8, Yagi Takao9, Kosaka Hiroaki1, Miyoshi Hideto10, Harada Shigeharu4, Kita Kiyoshi2,3, Hirano Katsuya1 (1.Dept. of Cardiovascular Physiol., Fac. of Med., Kagawa Univ., 2.Dept. of Biomed. Chem., Grad. Sch. of Med., The Univ. of Tokyo, 3.Sch. of Trop. Med. and Glob. Health, and Inst. of Trop. Med., Nagasaki Univ., 4.Dept. of Appl. Biol., Grad. Sch. of Sci. and Tech., Kyoto Inst. of Tech., 5.Div. of Mol. Biosci., Memb. Prot. Crystallogr. Group, Imperial Coll., 6.Memb. Prot. Lab., Diamond Light Sour., 7.Dept. of Cell Biol., Grad. Sch. of Med., Kyoto Univ., 8.Sys. and Struc. Biol. Center, RIKEN, 9.Dept. of Mol. and Experiment. Med., The Scripps Res. Inst., 10.Div. of Appl. Life Sci., Grad. Sch. of Agri., Kyoto Univ.)

The 91th Annual Meeting of JBS