The Molecular Biology Society of Japan

[2P-0098] Deubiquitylating enzyme USP42 localized to nuclear speckles regulates DNA double-strand break repair

Misaki Matsui1, Yusuke Kimura1, Masako Abe2, Shoki Kajita1, Wakana Torii1, Masamichi Ishiai2,3, Minoru Takata2, 〇Ryotaro Nishi4 (1.Biomed. Sci., Grad. Sch. Life Sci., Ritsumeikan Univ., 2.Radiat. Biol. Centre, Grad. Sch. Biostudies, Kyoto Univ., 3.Central Radioisotope Div., Ntl. Cancer Ctr. Res. Inst., 4.Dept. Biomed. Sci., College Life Sci., Ritsumeikan Univ.)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[2P-0101] Visualization and quantification of DNA double strand breaks in mouse fertilized oocytes using live-cell imaging

〇Miona Oguri1, Tetsuya Handa2, Yuka Suzuki1, Yu Hatano1, Mikiko Tokoro1,3, Tatsuma Yao1,4, Shouhei Kobayashi5, Yoshihiko Hosoi1, Naohito Nozaki6, Tokuko Haraguchi5, Hiroshi Kimura2, Kazuo Yamagata1 (1.BOST., Kindai Univ, 2.Cell Biol. Ctr, IIR, Tokyo Tech, 3.Asada Ladies Clinic, 4.R&D, Fuso Phama., Ltd, 5.Advanced ICT Res. Inst., NICT, 6.MAB Inst. Inc.)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[2P-0102] ATM regulates ARP8 phosphorylation to prevent etoposide-induced chromosomal translocations

〇Jiying Sun1, Lin Shi1, Aiko Kinomura1, Atsuhiko Fukuto1, Yasunori Horikoshi1, Yukako Oma2, Masahiko Harata2, Masae Ikura3, Tsuyoshi Ikura3, Roland Kanaar4, Satoshi Tashiro1 (1.Dept. of Cell. Biol., RIRBM, Univ of Hiroshima , 2.Lab. of Mol. Bio., Grad. Sch. of Agric. Sci, Univ of Tohoku, 3.RBC, Univ of Kyoto, 4.Dept. of Mol. Genetics, Oncode Inst., Erasmus MC)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[2P-0103] Heterochromatin suppresses gross chromosomal rearrangements at centromeres by repressing Tfs1/TFIIS-dependent transcription

〇Takuro Nakagawa1, Dayalini Weerasekara1, Jie Su1, Faria Zafar1, Tatsuro S Takahashi4, Hisao Masukata1, Takuya Kajitani2, Hiroshi Kimura3, Yota Murakami2, Akiko Okita1 (1.Dept of Biol Sci, Grad Sch of Sci, Osaka University, 2.Dept of Che, Fac of Sci, Hokkaido University, 3.Institute of Innovative Research, Tokyo Institute of Technology, 4.Dept of Biol, Fac of Sci, Kyushu University)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[2P-0105] Investigation of transcription complex 1 in response to DNA double strand break

〇Yoshihiko Hagiwara1, Yasuhara Takaaki2, Reona Kato2, Motohiro Yamauchi3, Hiro Sato1, Takahiro Oike1, Takashi Nakano1, Atsushi Shibata4 (1.Dept of Rad Onco, Grad Sch of Med, Univ of Gunma, 2.Lab of Mol Rad, Cent for Disease Biol and Integ Med, Univ of Tokyo, 3.Div of Rad Biol and Protection, Atomic Bomb Disease Inst, Univ of Nagasaki, 4.Edu and Res Supp Center, Grad Sch of Med, Univ of Gunma)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[2P-0106(3PW-13-4)] Rad52 promotes XPG-mediated R-loop processing to initiate transcription-associated homologous recombination repair

〇Reona kato1, Takaaki Yasuhara1, Yoshihiko Hagiwara2, Bunsyo Shiotani3, Motohiro Yamauchi4, Shinichiro Nakada5, Atsushi Shibata2, Kiyoshi Miyagawa1 (1.Laboratory of Molecular Radiology, The University of Tokyo, 2.Education and Research Support Center, Gunma University, 3.Division of Cellular Signaling, National Cancer Center Research Institute, 4.Division of Radiation Biology and Protection, Atomic Bomb Disease Institute, Nagasaki University,, 5.Department of Bioregulation and Cellular Response, Graduate School of Medicine, Osaka University)

The 41st Annual Meeting of the Molecular Biology Society of Japan