The Molecular Biology Society of Japan

[1LBA-109] Novel mutants of α-synuclein that cause Parkinson's disease aggregated in HEK293 culture cells.

〇Yasutaka Fujii1, Mikiko Nakamura1, Ayako Suzuki1, Tomoyuki Yoshida2, Hisashi Hoshida1,3,4, Hisashi Mori2, Rinji Akada1,3,4 (1.Graduate School of Sciences and Technology for Innovation, Yamaguchi University, 2.Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 3.Yamaguchi University Research Center for Thermotolerant Microbial Resources, 4.Yamaguchi University Biomedical Engineering Center)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[1LBA-112] The trans isomer of Tau peptide is prone to aggregate, and WW domain of Pin1 drastically decreases its aggregation

〇Teikichi Ikura1, Naoya Tochio2,3, Ryosuke Kawasaki4, Mizuki Matsuzaki5, Akihiro Narita5, Mahito Kikumoto5, Naoko Utsunomiya Tate3, Shin-ichi Tate2,4, Nobutoshi Ito1 (1.Med Res Inst, Tokyo Med & Dent Univ, 2.RcMcD, Hiroshima Univ, 3.Fac of Pharm-Sci, Teikyo Univ, 4.Dept of Math & Life Sci, Grad Sch of Sci, Hiroshima Univ, 5.Struct Biol Res Center, Grad Sch of Sci, Nagoya Univ)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[1LBA-113] Role of ESCRT component CHMP2B in tau accumulation

〇Akiko Asada1,2, Keiya Ito2, Taro Saito1,2, Shin-ichi Hisanaga1,2, Koichi M. Iijima3,4, Kanae Ando1,2 (1.Department of Biological Sciences, Graduate School of Science and Engineering, Tokyo Metropolitan University, 2.Division of Biological Sciences, School of Science and Engineering, Tokyo Metropolitan University, 3.National Center for Geriatrics and Gerontology, Center for Development of Advanced Medicine for Dementia, Department of Alzheimer's Disease Research, 4.Graduate School of Pharmaceutical Sciences, Department of Experimental Gerontology, Nagoya City University)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[1LBA-114] Role of ESCRT complex in tau metabolism and toxicity

〇Keiya Ito1, Akiko Asada1,2, Taro Saito1,2, Shin-ichi Hisanaga1,2, Koichi Iijima3,4, Kanae Ando1,2 (1.Dept of Biol Sci, Univ of Tokyo Metropolitan Laboratory for. Molecular Neuroscience, 2.Dept of Biol Sci, Univ of Tokyo Metropolitan Graduate School of Science and Engineering, 3.Dept of AD Research, National Center for Geriatrics and Gerontology, Center for Development of Advanced Medicine for Dementia, 4.Dept of Experimental Gerontology, Graduate School of Pharmaceutical Sciences, Univ Nagoya City)

The 41st Annual Meeting of the Molecular Biology Society of Japan