[1SP-11-13_1P-880] Hypoxic stress decreases CD38 expression via up-regulation of microRNA-26 in multiple myeloma

^○Sayaka Iwama¹, Akihiro Kitadate², Yuto Takahashi¹, Wataru Kuroki², Masahiro Yamada², Naoto Takahashi² (1.Dept. of Life Sci., Grad. Sch. of Eng. Sci., Univ. of Akita, 2.Dept. of Hematology, Nephrology, and Rheumatology, Grad. Sch. of Med., Univ. of Akita)

The 46th Annual Meeting of the Molecular Biology Society of Japan |Wed. Dec 6, 2023 2:21 PM - 2:24 PM

[1SP-11-14_1P-876] Inhibition of glutamate dehydrogenase, not glutaminase shows high efficacy to NSCLC cells that exhibit tolerance to Osimertinib.

^○Taichi Oshima, Kenta Furuichi, Kousei Ito, Shigeki Aoki (Lab. of Biopharm., Grad. Sch. of Pharm. Sci., Chiba Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan |Wed. Dec 6, 2023 2:24 PM - 2:27 PM

[1SP-11-15_1P-872] Development of a novel co-culture system to mimic the characteristics of pancreatic ductal adenocarcinoma in vitro

^○Tatsuya Kometani^1,2, Koki Kamo^2,3, Keisuke Sekine² (1.Dept. Nutritional Science and Food Safety, Tokyo University of Agriculture, 2.Lab. of Cancer Cell Systems, National Cancer Center Research Institute, 3.Dept. Bioscience, Tokyo University of Agriculture)

The 46th Annual Meeting of the Molecular Biology Society of Japan |Wed. Dec 6, 2023 2:27 PM - 2:30 PM

[1SP-11-16_1P-870] Augmentation of anti-tumor effects of receptor-retargeted oncolytic herpes simplex virus (RR-oHSV) through introduction of syn mutations

^○Takuma Suzuki¹, Hideaki Tahara², Hiroaki Uchida¹ (1.Tokyo Univ. of Pharm. and Life Sci., 2.Osaka Int. Cancer Ctr)

The 46th Annual Meeting of the Molecular Biology Society of Japan |Wed. Dec 6, 2023 2:30 PM - 2:33 PM

[1SP-11-17_1P-860] Development of MCM8-9 inhibitory aptamers with artificial nucleic acids

^○Yuki Uchibori¹, Yuya Kasahara², Kouta Mayanagi³, Masatoshi Fujita¹ (1.Dept. of Cellular Biochem., Grad. Sch. Pharm. Sci., Kyushu Univ., 2.NIBIOHN, 3.Dept. of Drug Disc. Str. Biol., Grad. Sch. Pharm. Sci., Kyushu Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan |Wed. Dec 6, 2023 2:33 PM - 2:36 PM

[1SP-11-18_1P-866] Development of a CRISPR system that distinguishes single nucleotide mutations in the TERT promoter to suppress carcinogenesis.

^○Taku Yunomae², Hiromu Matsui¹, Yoshiaki Kobayashi², Kumiko UiTei³ (1.Dept. of Bioinfo and Sys., Fac. of Sci., Univ. of Tokyo, 2.Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo, 3.Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo/Dept. of Bioinfo and Sys., Fac. of Sci., Univ. of Tokyo)

The 46th Annual Meeting of the Molecular Biology Society of Japan |Wed. Dec 6, 2023 2:36 PM - 2:39 PM

[2SP-01-01_2P-004] Allele-specific, monoallelic gene expression experimental model utilizing mouse ES cell lines established from F1 blastocysts obtained by crossbreeding inbred mouse strains of different sub-species.

^○Ayaka Saito¹, Ryosuke Tahara¹, Michiko Hirose², Masayo Kadota³, Ayumi Hasegawa², Shinji Kondo⁴, Hidemasa Kato⁵, Takanori Amano⁶, Atsushi Yoshiki³, Atsuo Ogura², Hidenori Kiyosawa¹ (1.Lab. for Genome Sci., Dept. of Life Sci., ChibaTech, 2.Bioresource Engineering Division, RIKEN BRC, 3.Experimental Animal Division, RIKEN BRC, 4.Genome Science Center, ROIS, 5.Dpt Dev Biol and Funct Genom, Grad Sch of Med, Ehime Univ., 6.Next Generation Human Disease Model Team RIKEN BRC)

The 46th Annual Meeting of the Molecular Biology Society of Japan |Thu. Dec 7, 2023 1:45 PM - 1:48 PM

[2SP-01-02_2P-034] Analysis of nucleic acid structures associated with cerebellar ataxia, neuropathy, vestibular areflexia syndrome（CANVAS）

^○Kenta Kudo^1,2, Karin Hori¹, Sefan Asamitsu³, Maeda Kohei^1,2, Yukari Aida^1,2, Mei Hokimoto^1,2, Norifumi Shioda^1,2 (1.Dept. of Geno. Neu., IMEG, Kumamoto Univ., 2.Grad. Sch. of Pharma. Sci., Kumamoto Univ., 3.RIKEN IMS)

The 46th Annual Meeting of the Molecular Biology Society of Japan |Thu. Dec 7, 2023 1:48 PM - 1:51 PM

[2SP-01-04_2P-028] REPrise: De novo interspersed repeat detection using inexact seed

^○Atsushi Takeda^1,2, Daisuke Nonaka³, Yuta Imazu³, Tsukasa Fukunaga¹, Michiaki Hamada^1,2 (1.Waseda Univ., 2.AIST・Waseda CBBD-OIL, 3.Univ. of Tokyo)

The 46th Annual Meeting of the Molecular Biology Society of Japan |Thu. Dec 7, 2023 1:54 PM - 1:57 PM

[2SP-01-05_2P-026] Evaluation of the involvement of mTOR signaling in the pathophysiology of Fuchs endothelial corneal dystrophy

^○Suguru Ito¹, Naoki Okumura¹, Koki Amano¹, Ayaka Izumi², Yuki Oyama^3,4, Masahito Ikawa^3,4, Noriko Koizumi¹ (1.Dept. of Biomedical Engineering, Doshisha Univ., 2.AE Inc., 3.Grad. Sch. of Pharmaceutical Sciences., Osaka Univ., 4.RIMD, Osaka Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan |Thu. Dec 7, 2023 1:57 PM - 2:00 PM