[29-211-pm] Nucleic acids

Fri. Mar 29, 2024 2:27 PM - 3:15 PM [Room 211] Conference Center 211+212 (2F)

Chair: Masami Nagahama, Hidenori Tani

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2:27 PM - 2:39 PM

[29-211-pm07] Mechanism of mRNA degradation by CCR4-NOT complex

○SATOSHI HASHIMOTO¹, Jennifer SAUERLAND², Hideaki TAKEDA¹, Toshifumi INADA¹ (1. Institute of Medical Science University of Tokyo, 2. University of Heidelberg)

2:39 PM - 2:51 PM

[29-211-pm08S] Effect of chemical modifications on the cytotoxicity of long-stranded DNA duplexes

○Manami Baba¹, Kunihiko Morihiro¹, Akimitsu Okamoto¹ (1. Grad. Sch. Eng., UTokyo)

2:51 PM - 3:03 PM

[29-211-pm09] Modulation of Gapmer-ASO toxicity by incorporation of acyclic artificial nucleic acids

○Jumpei Ariyoshi¹, Masaya Higuchi², Saki Imamura¹, Ayano Otsuka¹, Mioka Okuno¹, Nozomi Tanigawa¹, Ayaka Minamikawa¹, Hiroyuki Oyama¹, Hiroyuki Asanuma², Yukiko Kamiya^1,2 (1. Kobe Pharm. Univ., 2. Nagoya Univ.)

3:03 PM - 3:15 PM

[29-211-pm10S] Cytotoxicity induced by cancer cell-selective heteroduplex nucleic acid construction

○Naoki Harada¹, Kunihiko Morihiro¹, Akimitsu Okamoto¹ (1. Grad. Sch. Eng., The Univ. of Tokyo)