[1P-261] NRF3-POMP-20S proteasome axis enhances tumor growth

^○Waku Tsuyoshi¹, Kobayashi Akira^1,2 (1.Sch. Life & Med. Sci., Doshisha Univ., 2.Grad. Sch. Life & Med. Sci., Doshisha Univ.)

The 91th Annual Meeting of JBS

[1P-262(1T14a-06)] Metabolic reprogramming in cancer cells is regulated by tumor associated-antigen

^○Takamiya Rina¹, Soga Tomoyoshi², Suzuki Hiromu³, Ohtsubo Kazuaki⁴ (1.Lab. of Microenv. Metab. Health Sci., Grad. Sch. of Med., Univ. of Tokyo, 2.Inst. Adv. Biosci., Keio Univ., 3.Mol. Biol., Sapporo Med. Univ., 4.Dept. of Anal. Biochem., Fac. of Life Sci., Kumamoto Univ.)

The 91th Annual Meeting of JBS

[1P-263] Roles of aldo-keto reductase 1C3 and ABC transporter B1 in development of irinotecan resistance in colon cancer cells

^○Matsunaga Toshiyuki¹, Okumura Naoko¹, Iguchi Kazuhiro², Endo Satoshi¹, Ikari Akira¹ (1.Laboratory of Biochemistry, Gifu Pharmaceutical University, 2.Laboratory of Community Pharmacy, Gifu Pharmaceutical University)

The 91th Annual Meeting of JBS

[1P-264] Mechanism of growth inhibitory effect by Tamoxifen on Paget cells

^○Akatsuka Kotomi¹, Higo Narumi², Nakashima Yuichi¹, Hasegawa Go³, Shimonaka Motoyuki³ (1.Dept. of Chem., Grad. Sch. of Sci., Tokyo Univ. of Sci., 2.Dept of Appl. Chem., Fac. of Sci., Tokyo Univ. of Sci., 3.Dept of Chem., Fac. of Sci., Tokyo Univ. of Sci.)

The 91th Annual Meeting of JBS

[1P-265] Altered splicing of RhoA is associated with abrogation of its expression and activity in diffuse-type gastric carcinoma cells

^○Miyamoto Shingo¹, Nakabo Ayaka^1,2, Fukami Kiyoko², Yanagihara Kazuyoshi³, Sakai Ryuichi⁴, Yamaguchi Hideki¹ (1.Department of Cancer Cell Research, Sasaki Institute, Sasaki Foundation, 2.Laboratory of Genome and Biosignals, Tokyo University of Pharmacy & Life Sciences, 3.Division of Biomarker Discovery, EPOC, National Cancer Center, 4.Division of Biochemistry, Kitasato University School of Medicine)

The 91th Annual Meeting of JBS

[1P-266(1T14a-01)] Design of MMP-9-selective inhibitor and its effect on MMP-9-stimulated tumor cell invasion

^○Takizawa Ko, Higashi Shouichi (Graduate School of Nanobioscience, Yokohama City University)

The 91th Annual Meeting of JBS

[1P-267] Mechanistic analysis of FABP5-dependent promotion of invasive activity in colorectal cancer cells

^○Kobayashi Narumi¹, Senga Shogo², Kawaguchi Koichiro³, Fujii Hiroshi⁴ (1.Dept.of Biomed. & Eng., Interdisci.Grad.Sch of Sci. & Technol., Shinshu Univ., 2.Dept.of Bioscience & Food Production, Interdisci.Grad.Sch of Sci. & Technol., Shinshu Univ., 3.National Center for Geriatrics and Gerontology, 4.Dept. of Interdisci. Genome Sci.&Cell Met., Inst.for Biomed.Sci. (IBS), Interdisci. Cluster for Cutting Edge Res. (ICCER), Shinshu Univ.)

The 91th Annual Meeting of JBS

[1P-268] Analysis of FABP5-dependent transition promotion mechanism in cancer cells

^○Ando Akira¹, Senga Syogo², Fujii Hiroshi³ (1.Dept.of Biomed. & Eng., Interdisci.Grad.Sch of Sci. & Technol., Shinshu Univ., 2.Dept.of Bioscience & Food Production, Interdisci.Grad.Sch of Sci. & Technol., Shinshu Univ., 3.Dept. of Interdisci. Genome Sci.&Cell Met., Inst.for Biomed.Sci. (IBS), Interdisci. Cluster for Cutting Edge Res. (ICCER), Shinshu Univ.)

The 91th Annual Meeting of JBS

[1P-269(1T14a-07)] Down-regulation of the negative regulator of NF-κB, p47, via the autophagy enhances the NF-κB signaling and induces CADM1 overexpression in ATL

^○Nakahata Shingo¹, Sarkar Bidhan¹, Nishikata Ichiro¹, Ichikawa Tomonaga¹, Fujii Masahiro², Inoue Jun-ichiro³, Iha Hidekatsu⁴, Shimoda Kazuya⁵, Morishita Kazuhiro¹ (1.Division of Tumor and Cellular Biochemistry, Department of Medical Sciences, Faculty of Medicine, University of Miyazaki, 2.Division of Virology, Niigata University Graduate School of Medical and Dental Sciences, 3.Division of cellular and molecular Biology, Institute of Medical Science, University of Tokyo, 4.Department of Microbiology, Oita University, 5.Division of Gastroenterology and Hematology, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki)

The 91th Annual Meeting of JBS

[1P-270(1T14a-02)] Development of anti-metastaic drugs based on inhibition of MMP-7-induced cancer cell aggregation

^○Ito Saki, Ishikawa Tomohiro, Higashi Shouichi (Graduate School of Nanobioscience, Yokohama City University)

The 91th Annual Meeting of JBS