[1P-004] BRCC36 associates with FLT3-ITD to regulate its protein stability and intracellular signaling in acute myeloid leukemia

^〇Jianwei Liu¹, Tomoya Isaji¹, Sachiko Komatsu², Yuhan Sun¹, Xing Xu¹, Tomohiko Fukuda¹, Tsutomu Fujimura², Shinichiro Takahashi³, Jianguo Gu¹ (1.Institute of Molecular Biomembrane and Glycobiology, Tohoku Medical and Pharmaceutical University, 2.Division of Bioanalytical Chemistry, Tohoku Medical and Pharmaceutical University., 3.Division of Laboratory Medicine, Faculty of Medicine, Tohoku Medical and Pharmaceutical University.)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-005(1T02a-01)] Exogenous L-Fucose attenuates neuroinflammation induced by lipopolysaccharide in Fut8 heterozygous knockout mouse

^〇Xing Xu¹, Tomohiko Fukuda¹, Jun Takai², Miyako Nakano³, Takashi Moriguchi², Jianguo Gu¹ (1.Tohoku Medical and Pharmaceutical University, Institute of Molecular Biomembrane and Glycobiology, 2.Tohoku Medical and Pharmaceutical University, Graduate School of Medicine, 3.Hiroshima University, Graduate School of Integrated Sciences for Life)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-006] Focal adhesion kinase regulates the sialylation of N-glycans through the PI4KIIα-PI4P pathway

^〇Yuhan Sun¹, Tomoya Isaji¹, Nobuaki Miura², Jun-ichi Furukawa^3,4, Tomohiko Fukuda¹, Jianguo Gu¹ (1.Tohoku Medical and Pharmaceutical University, Institute of Molecular Biomembrane and Glycobiology, 2.Niigata University Graduate School of Medical and Dental Sciences, Division of Bioinformatics, 3.Hokkaido University Graduate School of Medicine, Department of Orthopedic Surgery, 4. Tokai National Higher Education and Research System, Division of Glyco-Systems Biology)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-007] Quality control of proteins containing epidermal growth factor-like (EGF) repeats by xylosyl-extension of O-glucose glycans

^〇Yukihiro Mita^1,2, Yohei Tsukamoto¹, Wataru Saiki¹, Yusuke Urata³, Yuuki Kurebayashi⁵, Akira Minami⁵, Tadanobu Takahashi⁵, Hideharu Hibi^2,3, Tetsuya Okajima^1,4, Hideyuki Takeuchi^4,5 (1.Department of Molecular Biochemistry, Nagoya University Graduate School of Medicine, 2.Department of Oral and Maxillofacial Surgery, Nagoya University Graduate School of Medicine, 3.Department of Oral and Maxillofacial Surgery, Nagoya University Hospital, 4.Institute for Glyco-core Research Tokai National Higher Educational and Research System, 5.Department of Biochemistry, University of Shizuoka School of Pharmaceutical Sciences)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-008] function of N-glycans in the molecular stability of ErbB2 (HER2)

^〇Naoki Fujitani¹, Yasuaki Uehara¹, Yoshihiro Hasegawa¹, Ukichiro Hashimoto¹, Shigeru Ariki^1,2, Motoko Takahashi¹ (1.Department of Biochemistry, Sapporo Medical University School of Medicine, 2.Department of Chemistry, Center for Medical Education, Sapporo Medical University, Sapporo, Japan.)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-009] N-glycosylation of FGFR3 regulates the expression to the plasma membrane and its activity.

^〇Ukichiro Hashimoto¹, Naoki Fujitani¹, Yasuaki Uehara¹, Yoshihiro Hasegawa¹, Shigeru Ariki², Motoko Takahashi¹ (1.Department of Biochemistry, Sapporo Medical University School of Medicine, 2.Department of Chemistry, Center for Medical Education, Sapporo Medical University)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-010] Identification of sperm-binding site in the hinge region of bovine zona pellucida glycoprotein ZP4

^〇Yulin Zhang¹, Dilimulati Kamila², Tianchen Wang¹, Fabiana Lica Imai², Naoto Yonezawa² (1.Graduate School of Integrated Science and Engineer, Chiba University, 2.Graduate School of Science, Chiba University)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-011] Analysis of the polysialic acid expression in mouse brain during aging

^〇Ayane Naramura^1,2, Masaya Hane^1,2,3, Hirotake Nihei^1,2, Chikara Abe³, Di Wu^1,2,3, Ken Kitajima^1,2,3, Chihiro Sato^1,2,3 (1.Biosci. Biotech. Center, Nagoya Univ., 2.Grad. Sch. Bioagr. Sci., Nagoya Univ., 3.iGCORE, Nagoya Univ.)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-012] Applications of fucoidans in oral healthcare: use of pharmacologically active ingredient derived from seaweed

^〇Shunya Oka¹, Shuichi Tsubura^2,3, Akane Imai^2,4 (1.Department of Biology, School of Life Dentistry at Niigata, The Nippon Dental University, 2.Department of Biochemistry, School of Life Dentistry at Niigata, The Nippon Dental University, 3.Tsubura Dental Clinic, 4.Department of Dental Hygiene, The Nippon Dental University College at Niigata)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-013] Comprehensive analysis of O-Glucose Glycan Modifications on the endogenous NOTCH2 by Glycoproteomics

^〇Koki Kato¹, Yuuki Kurebayashi¹, Yohei Tsukamoto², Akira Minami¹, Tadanobu Takahashi¹, Tetsuya Okajima^2,3, Hideyuki Takeuchi¹ (1.Sch. Pharm. Sci., Shizuoka Univ., 2.Grad. Sch. Med., Nagoya Univ., 3.iGCORE, Nagoya Univ.)

The 96th Annual Meeting of the Japanese Biochemical Society