[1P-852] Wnt activation disturbs cell competition and causes diffuse invasion of transformed cells through NF-κB-MMP21 pathway

^○Kazuki Nakai¹, Hancheng Lin¹, Shinya Tanaka², Yoku Hayakawa³, Eilma Akter¹, Hitoshi Saitoh⁵, Akihiro Ohashi⁵, Yasuyuki Fujita⁴, Shunsuke Kon¹ (1.Div. of Mol. Biol., Div. of Cancer Cell Biol., RIBS., TUS., 2.Div. of Mol. Oncology, IGM., Hokkaido Univ., 3.Dept. of Gastroenterology, Univ. of Tokyo, 4.Dept. of Molecular Oncology, Grad. Sch. of Med., Kyoto Univ., 5.Div. of Collaborative Research and Developments, EPOC., NCC.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-853] The Effects of low molecular weight fucoidan extract on multidrug resistance of cancer cells

^○Atomu Anai¹, Koichi Okawachi², Hiroshi Eto³, Kiichiro Teruya^4,1,2 (1.Grad. Sch. Sys. Life Sci., Kyushu Univ., 2.Grad. Sch. Biores. Bioenv. Sci. Kyushu Univ., 3.Daiichi Sangyo Co., Ltd., 4.Fac. Agr., Kyushu Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-854] Repeat elements enriched in cis-regulatory regions act in cancer cell transition to estrogen-independence

^○Shengliang Ni¹, Xufeng Shu^1,2, Masaki Kato², Noriko Saitoh³, Martin Frith^1,4 (1.Dept. of CBMS, Grad. Sch of Fron. Sci., Univ. of Tokyo, 2.RIKEN, 3.Div. of Cancer Biology, The Cancer Institute of JFCR, 4.AIST)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-855] Development of evaluation model of flow cytometry for combination effects of anti-cancer agents using machine learning

^○Koki Murayama¹, Ying Tong¹, Barkha Saraswat¹, Kohei Hayashi^1,2, Mitsuko Masutani¹ (1.Dept. Molecular & Genomic Biomed., CBMM, Grad. Sch. Biomed. Sci., Nagasaki Univ., 2.Department of Gastroenterology and Hepatology, Nagasaki Univ. Hospital)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-856_1SP-11-06] Use of tumor-homing cellular carriers for anticancer virus to disseminated cancer treatment

^○Yuya Takeuchi^1,2, Emiko SonodaFukuda², Nao Ogawa^1,2, Toru Takarada³, Noriyuki Kasahara⁴, Shuji Kubo² (1.Dept. of Biomed. Chem., Grad. Sch. of Sci. & Tech., Kwansei Gakuin Univ., 2.Lab. of Mol. & Genetic Therap., Advanced Med. Sci., Hyogo Med. Univ., 3.Lab. of Functional Mol. Chem., Kobe Pharm. Univ., 4.Dept. of Neuro. Surg. & Rad. Oncology, UCSF)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-857] Cell death-inducing cancer virotherapy for canine malignancies using retroviral replicating vector

^○Emiko SonodaFukuda¹, Yuya Takeuchi^1,2, Nao Ogawa^1,2, Toru Takarada³, Shunsuke Noguchi⁴, Noriyuki Kasahara⁵, Shuji Kubo¹ (1.Lab. of Mol. & Genetic Therap., Advanced Med. Sci., Hyogo Med. Univ., 2.Dept. of Biomed. Chem., Grad. Sch. of Sci. & Tech., Kwansei Gakuin Univ., 3.Lab. of Functional Mol. Chem., Kobe Pharm. Univ., 4.Lab. of Vet. Radio., Grad. Sch. of Vet. Sci., Osaka Metropolitan Univ., 5.Dept. of Neuro. Surg. & Rad. Oncology, UCSF)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-858_1SP-11-08] Functional analysis of transcription factor NRF3 as a novel tumor growth factor in pancreatic cancer

^○Katsuya Satoh¹, Takuto Michihara¹, Kohei Yamamoto², Ken Satoh¹, Mitsuyo Matsumoto³, kazuhiko Igarashi³, Tsuyoshi Waku², Akira Kobayashi¹ (1.Dept. of Med. Life Sys. Grad. Sch. of Life and Med. Sci., Doshisha Univ., 2.Dept. of Med. Life Sys., Fac. of Life and Med. Sci., Doshisha Univ., 3.Dept. of Biochem., Grad. Sch. Of Med. Tohoku Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-859] Spatial analysis of deconvolced cells in tumor microenvironment

^○Ange Yan (CB, GSFS, Univ. of Tokyo)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-860_1SP-11-17] Development of MCM8-9 inhibitory aptamers with artificial nucleic acids

^○Yuki Uchibori¹, Yuya Kasahara², Kouta Mayanagi³, Masatoshi Fujita¹ (1.Dept. of Cellular Biochem., Grad. Sch. Pharm. Sci., Kyushu Univ., 2.NIBIOHN, 3.Dept. of Drug Disc. Str. Biol., Grad. Sch. Pharm. Sci., Kyushu Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-861_1AS-05-06] Elucidation of intratumoral cellular diversity and the role of ROR1^high tumor-initiating cells in pancreatic cancer.

^○Masaya Yamazaki¹, Shinjiro Hino², Shingo Usuki⁴, Mitsuyoshi Nakao², Takaaki Ito³, Kazuya Yamagata¹ (1.Dept. Med. Biochem., Grad. Sch. Med. Sci., Kumamoto Univ., 2.Dept. Med. Cell. Biol., IMEG., Kumamoto Univ, 3.Dept. Med. Technol., Facul. Health Sci., Kumamoto Health Science Univ., 4.LILA., IMEG., Kumamoto Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan