[1P-923] rGONAD: a new method for genome-editing in rats and the creation of rat models of X-linked Alport syndrome

^○Masumi Namba, Tomoe Kobayashi, Mayumi Kohno, Takayuki Koyano, Makoto Matsuyama (Division of Molecular Genetics, Shigei Medical Reserch Institute)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-924] Genetic basis of Japanese patients with hypogonadotropic hypogonadism

^○Ikuko Kageyama¹, Erina Suzuki¹, Keiko Matsubara^1,2,3, Yoko Kuroki^2,3,4, Tsutomu Ogata⁵, Maki Fukami^1,2 (1.Dept. of Mol. Endocrinol., NCCHD, 2.Div. of Diversity Research, NCCHD, 3.Div. of Collaborative Research, NCCHD, 4.Dept. of Genome Med., NCCHD, 5.Dept. of Pediatrics, Hamamatsu Univ. School of Medicine)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-925] Does Ncor1 mutation promote tumorigenesis?

^○Misato Kimura, masaki ohmuraya, Yoshie Yoshikawa (Dept. of Genetics, Sch. of medicine, Univ. of Hyogo medical)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-926] Establishment of a Drosophila model of CMT by targeting PNKP

^○HYUGA YOSHIKAWA (Dept. of Appl. Biol., Kyoto Inst. of Technol.,)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-927] Identification and phenotypic analysis of a novel imprinted gene in the mouse Prader-Willi syndrome critical region

^○Tatsuya Kishino (Div. of Func. Genet.,Grad. Sch. of Biomed.Sci., Nagasaki Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-928] Identification of factors genetically interact with Drosophila homolog Pgk of Parkinson’s disease candidate gene PGK1 and elucidation of the mechanism of the interactions

^○Kotomi Okuno¹, Takashi Kasai², Hideki Yoshida¹ (1.Dept.of Appl.Biol.,Kyoto Inst. of Technol.,, 2.Dept.of Neurology,Kyoto Pref. Univ. of Med.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-929] Development of detection system for Mulberry body which is biomarker of Fabry disease

^○Haruna OTA¹, Daimei MIURA¹, Kensuke HIRANO², Harune SUZUKI¹, Kaori TSUKAKOSHI¹, Wakako TSUGAWA^1,2, Ryutaro ASANO^1,3, Ryuji KAWANO¹, Satomi ASAI⁴, Kazunori IKEBUKURO¹ (1.Dept. of Biotechnol., Grad. Sch. of Eng., Tokyo Univ. of Agric. and Technol., 2.Dept. of Ind. Technol. and Innovation, Grad. Sch. of Eng., Tokyo Univ. of Agric. and Technol., 3.Inst. of Global Innovation Research, Tokyo Univ. of Agric. and Technol., 4.Dept. of Laboratory Medicine, School of Medicine, Tokai Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-930] The impairment in subcellular localisation of c-KIT and GDF9 caused by the loss of a complex membrane trafficking factor component in oocyte

^○Chi Nguyen¹, Woojin Kang², Sugiyama Fumihiro², Mizuno Seiya² (1.PhD. Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba, 2.Laboratory Animal Resource Center and Trans-Border Medical Research Center, University of Tsukuba)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-931] Autosomal dominant caspase activation and recruitment domain 11 (CARD11) loss-of-function impairing NFB signaling cause hyper-IgE, immunodeficiency, and severe atopic disease

^○DarShong Lin¹, TsuYen Wu², KuoRay Lin³, Jeffrey J.Y. Yen³ (1.Dept. of Pediatric Genetics, MacKay Memorial Hospital, Taipei, Taiwan, 2.Dept. Medical Research, MacKay Memorial Hospital, Taipei, Taiwan, 3.Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-932] Familial retinitis pigmentosa with neuromuscular symptoms carrying a novel nonsense variant in RDH11

^○Shigeyoshi Hiruki¹, Shiroh Miura², Saho Fujishita², Hiroki Shibata¹ (1.Div. of Genomics, Med. Inst. of Bioreg., Kyushu Univ., 2.Dept of Neurol. and Geriatr. Med., Ehime Univ. Grad. Sch. of Med.)

The 46th Annual Meeting of the Molecular Biology Society of Japan