[2P-130] Exploring ES cells that reflect differentially expressed gene expression in blastocysts derived from in vitro or in vivo developmental origin

^○ARISA FUTONO¹, AYAKA SAITO¹, MICHIKO HIROSE², MASAYA KADOTA³, AYUMI HASEGAWA², TAKANORI AMANO⁴, ATSUSHI YOSHIKI³, ATSUO OGURA², HIDENORI KIYOSAWA¹ (1.Lab. for Genome Sci., Dept. of Life Sci., ChibaTech, 2.Bioresource Engineering Division, RIKEN BRC, 3.Experimental Animal Division, RIKEN BRC, 4.Next Generation Human Disease Model Team RIKEN BRC)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-131] Roles of the histone variant H2A.Z in gonad maintenance of Caenorhabditis elegans

^○Natsumi Horii¹, Saho Kitagawa³, Nami Haruta², Masato Kanemaki⁴, Asako Sugimoto², Masahiko Harata¹ (1.Dept. of Biol. Mol., Grad. Sch. of Agr., Univ. of Tohoku, 2.Dept. of Dev. Dyn, Grad. Sch. of Life Sci., Univ. of Tohoku, 3.NanoLSI., Univ. of Kanazawa, 4.Mol. Cell Eng., Nat. Inst. of Gen.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-132_2AS-05-05] Transcriptional regulation of the natriuretic peptide gene during fetal life and heart failure.

^○Hijiri Inoue¹, Ken Matsuoka², Hyejin Jo¹, Osamu Tsukamoto³, Seiji Takashima^1,2 (1.Dept. of Med. Bio., Grad. Sch. of Fro Bio., Univ. of Osaka, 2.Dept. of Med. Bio., Grad. Sch. of Med., Univ. of Osaka, 3.Dept. of Bio. chem., Grad. Sch. of Med., Univ. of Hyogo Med)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-133] Structural mechanism of gene transcriptional repression mediated by histone H3 lysine 27 crotonylation

^○Tsuyoshi Konuma (Grad. Sch. of Med. Life Sci., YCU)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-134] Identification and functional analysis of MIWI2-associated proteins in mouse fetal testis.

^○Kanako Kita^1,2, Satomi Miyagawa¹, Manabu Nakayama³, Jacobsen Steven⁵, Haruhiko Koseki⁴, Toru Nakano^1,2 (1.Med. Sch., Univ. of Osaka, 2.Grad. Sch. of Frontier Biosci., Univ. of Osaka, 3.Lab. of Med. Omics Res., Dept. of Frontier Res. and Dev., Kazusa DNA Res. Inst., 4.RIKEN Center for Integrative Med. Sci., 5.Dept. of Mol., Cell, and Dev. Biol., Univ. of California)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-135] Screening for inhibitors of histone methyltransferase SETDB1

^○Kodai Kato^1,2, Yuki Maemoto¹, Iku Kuwahara², Takeshi Sonoda², Akiko Idei², Hiroyuki Osada³, Yoichi Shinkai⁴, Minoru Yoshida^2,5, Akihiro Ito^1,5 (1.Sch. of Life Sci., Tokyo Univ. of Pharm. and Life Sci., 2.Drug Dis. Seed Comp. Expl. Unit, RIKEN CSRS, 3.Chem. Resource Dev. Res. Unit, RIKEN CSRS, 4.Cell. Memory Lab., RIKEN CPR, 5.Chem. Genomics Res. Gr., RIKEN CSRS)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-136_1PS-18-05] The catalytic domain of histone methyltransferase SETD1A is required for cell fate determination in normal hematopoiesis

^○Makoto Matsumoto¹, Ryouji Fujiki¹, Mayumi Hirakawa², Tomokatsu Ikawa², Atsushi Iwama³, Kimi Araki⁴, Atsushi Kaneda¹, Takayuki Hoshii¹ (1.Dept. of Mol. Oncol., Grad Sch. of Med., Univ. of Chiba, 2.Div. of Immun., Grad. Sch. of Biol. Sci., Sci. Univ. of Tokyo, 3.Div. of Mol. Med., Inst. of Med. Sci., Univ. of Tokyo, 4.Div. of Dev. Gen., Inst. of Res. Dev., Univ. of Kumamoto)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-137] Structural Dynamics Following Strand Breaks in Bent Double-Stranded DNA

^○Riko Katayama¹, Takeru Kameda¹, Yuichi Togashi^2,1 (1.Coll. Life Sci., Ritsumeikan Univ., 2.RIKEN BDR)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-138_1PS-12-02] How is histone acetylation propagated in metazoans?

^○Takashi Umehara¹, Masaki Kikuchi¹, Satoshi Morita¹, Masatoshi Wakamori¹, Shin Sato¹, Tomomi UchikuboKamo¹, Takehiro Suzuki², Naoshi Dohmae², Mikako Shirouzu¹ (1.RIKEN BDR, 2.RIKEN CSRS)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-139] SETD1A-SOX2 axis is involved in tamoxifen resistance in estrogen receptor a-positive breast cancer cells

^○MINGLI JIN (Biol. Sci., Univ. of Gachon)

The 46th Annual Meeting of the Molecular Biology Society of Japan