[2P-452_2AS-11-04] The spatial scaling of Aurora B activity depends on HP1-mediated whole structural change of INCENP

^○Kosuke Sako¹, Noriyuki Kodera², Toru Hirota¹ (1.Div. Exp. Path. Cancer Inst., JFCR, 2.NanoLSI, Kanazawa Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-453_1PS-14-03] Centromeric non-coding RNA regulates chromosomal segregation

^○Saho Matsui^1,2, Ryusuke Nozawa¹, Toru Hirota^1,2 (1.Div. Exp. Pathol. Cancer Inst. JFCR, 2.Dept. JFCR., Tokyo Med. & Dent. Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-454] Activation of the WDR1 gene by deregulated E2F1 forms positive feedback loop in tumor suppressive E2F1 activity

^○MASHIRO SHIRASAWA, KIYOSHI OHTANI (Dept. of Biomed. Chem. Grad. Sch. of Sci. and Tech. Kwansei Gakuin Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-455] Elucidation of function of High Mobility Group Box 1 (HMGB1) in the skin∼The effects of A-box, an antagonist of HMGB1∼

^○Mizuki Okubayashi¹, Yohei Hirai² (1.Dept. of Biomed. Sci., Grad. Sch. of Sci., Univ. of Kwansei Gakuin, 2.Sch. of Biol. Envi., Univ. of Kwansei Gakuin)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-456] JLP overexpression induces chromosomal instability

^○Ryusuke Suzuki, Takeshi Suzuki, Katsuji Yoshioka (Div. Func. Gen., Cancer Res. Inst., Kanazawa Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-457] Whole-cell modeling of Escherichia coli from its genome sequence

^○Kazunari Kaizu^1,2 (1.BDR, RIKEN, 2.ExCELLS, NINS)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-458] The TNK2 inhibitor XMD16-5 induces multinucleation and cell death in cancer cells

^○Mayu Murata, Ryoko Ota, Ryuzaburo Yuki, Youhei Saito, Yuji Nakayama (Dept. of Bio., Univ. of Pham. , Univ. of Kyoto Pharm)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-459_2AS-11-06] A stopwatch measures the duration of mitosis to protect from cell division defects

^○Franz Meitinger¹, Hazrat Belal¹, Robert Davis², Mallory Martinez², Andrew Shiau², Karen Oegema^3,2, Arshad Desai^2,3 (1.Okinawa Institute of Science and Technology, Okinawa, Japan, 2.Ludwig Institute for Cancer Research, La Jolla, USA, 3.Dept. of Cell and Dev. Biol., UCSD, La Jolla, USA)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-460] Identification of genes involved in the inhibition of cell proliferation by momilactone B

^○Ken Matsumoto^2,1, Rumi Kurokawa¹, Megumi Takase¹, Kazunori Okada³, Minoru Yoshida^1,2 (1.Chem. Genomics Res. Gr., RIKEN CSRS, 2.Drug Discov. Seed Cmpd. Exp. Unit, RIKEN CSRS, 3.Lab. Env. Biochem., AgTECH, Univ. of Tokyo)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-461] NuMA deficiency causes micronuclei via checkpoint-insensitive k-fiber minus-end detachment from mitotic spindle poles

^○Marvin van Toorn, Amy Gooch, Susan Boerner, Tomomi Kiyomitsu (Cell division dynamics unit, Okinawa Institute of Science and Technology)

The 46th Annual Meeting of the Molecular Biology Society of Japan