[2P-797_1PS-02-07] In precision-cut lung slices, PCLS of idiopathic pulmonary fibrosis model, bleomycin treatment causes perinuclear localization of gH2AX, resulting in more severe senescence.

^○Yoko Miura, Akiho Takata, Satoshi Kanazawa (Dept. of Neu. Disorder Genet.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-798_2SP-10-13] Age-dependent chemotaxis decline via nuclear hormone receptor NHR-76

^○Rikuou Yokosawa, Kentaro Noma (Dep. of Biol. Sci., Grad. Sch., Nagoya Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-799] Regulatory mechanisms of glucocorticoid hypersecretion in old mice.

^○Noriyuki Okudaira¹, MiHo Akimoto¹, Misato Terahara¹, Takao Susa¹, Miho Akimoto¹, Harumi Hisaki¹, Masayoshi Iizuka^1,2, Mimi TamamoriAdachi¹ (1.Dept. of Biochem., Teikyo Univ. Sch. of Med., 2.Dept. of Med. Edu. Cent., Teikyo Univ. Sch. of Med.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-800] Analysis of acetylated proteins in the skeletal muscle increased by aging and SIRT1 knockout.

^○Ryusuke Hosoda¹, Ryuta Nakashima¹, Naotoshi Iwahara², Iyori Nojima¹, Atsushi Kuno¹ (1.Dept. Pharmacol., Sch. Med., Sapporo Medical Univ., 2.Dept. Neurol., Sch. Med., Sapporo Medical Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-801] Screening for Ayurvedic herbs that prevent protein aggregation.

^○Kento Mizutani, Maiko Natsui, Yuki Takauji, Yoshimi Yamakami, Michihiko Fujii (Grad. Sch. of Nanobiosci. Yokohama City Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-802] High AGE diets cause the premature aging and fluctuations in gene expression

^○Hiroaki Iwasa¹, Eichi Watabe², Wataru Nishimura¹ (1.Dept. of Mol. Biol., Sch. of Med., Int’l Univ. of Health and Welfare, 2.Biz. Dev. Dept., Hitachi, Ltd. Healthcare Innovation Div.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-803_2AS-12-03] Senescent stromal cells support tumor progression of PDAC

^○TehWei Wang, Yue Zhang, Makoto Nakanishi (Divi. of Cancer cell biology, IMSUT)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-804] Suppression effect of sesamin on age-dependent impairement of protein homeostasis appears via stimulation of autophagy in Drosophila adult muscle

^○Yuka Yonezu, Le Tuan Dat, Mika Ozaki, Yoshihiro H. Inoue (Biomedical Res. Ctr., Kyoto Inst. Tech.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-805] Analysis of primary myofiber-derived extracellular vesicles in aging

^○Naoomi Tominaga, Yuta Miyagi (Div. of Clin. Lab. Sci., Grad. Sch. of Med., Yamaguchi Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[2P-806] The endogenous mesotrypsin inhibitor SerpinB12 is associated with skin aging, including stratum corneum thickening and dry skin

^○Masashi Miyai¹, Mami Yamamoto², Akira Matoyama¹, Junichiro Hiruma², Ryoji Tsuboi², Toshihiko Hibino^1,2 (1.Shiseido Co., Ltd., MIRAI Technology Institute, 2.Dept. of Dermatol., Tokyo Med. Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan