シンポジウム

[2S-Aa(English)] [Transformative Research Areas (A)] Mechanochemical crosstalk in multicellular movement during development([学変A] 発生における細胞集団運動を創発するメカノケミカルクロストーク)

2024年7月18日(木) 15:00 〜 17:30 A会場 (1F 大会議室101)

Organizers:Takayuki Suzuki(Osaka Metropolitan University), Hidehiko Hashimoto(Osaka University)

Multicellular movement underlies multicellular morphogenesis and homeostasis during development. While genetic programs pattern multicellular movements through biochemical signaling pathways that act within and between cells, it remains not fully elucidated how self-organized patterns of multicellular movements emerge from dynamic mechanochemical interactions across molecular, cellular and tissue scales. In this symposium, we aim to understand the common and divergent systems underlying the mechanism governing the emergence of patterns of multicellular movements during development through comparing studies across various tissues and animals.

+全てマイスケジュールに登録

Opening Remarks(はじめに)

Time Adjustment(時間調整)

[2A12] ‘Mechano-gradients’ drive morphogen-noise correction to ensure robust patterning(メカノ勾配によるモルフォゲンノイズ除去システムは組織パターン形成の頑強性を支える)

*Kana Aoki¹, Tohru Ishitani¹ (1. Dept. of Homeostatic Regulation, RIMD, Osaka Univ.)

[2A13] Mechanical transapical coupling of endometrial epithelial cells during implantation

*Jun Sakurai^1,2, Noriyuki Kinoshita^1,2, Tetsuhisa Otani⁴, Hiroshi Koyama^1,2, Mikio Furuse^3,2, Toshihiko Fujimori^1,2 (1. National Institute for Basic Biology, 2. SOKENDAI, 3. National Institute for Physiological Sciences, 4. Tokyo Metropolitan University)

[2A14] Mechanochemical control of digit emergence

*Carolina Parada¹ (1. Department of Developmental and Stem Cell Biology, Pasteur Institute, Paris, France)

[2A15] A physical role of epithelium in chick limb bud elongation(肢芽の遠近軸に沿った伸長に与える上皮の物理的役割の解明)

Kazuki Kawamura², Daisuke Ohtsuka³, Yoshihiro Morishita³, *Takayuki Suzuki¹ (1. Department of Biology, Faculty of Science, Osaka Metropolitan University, 2. Department of Biology, Faculty of Science, Nagoya University, 3. RIKEN, BDR)

[2A16] An optogenetic toolbox to manipulate integrin adhesion complexes.

Minggang Xiong¹, Tsun Lam Leong¹, *Heath Ellis Johnson¹ (1. The University of Hong Kong)

[2A17] Dynamic separation of cell-cell contacts induces RhoA and Myosin activity to drive zippering and neural tube closure in a simple chordate

*Hidehiko Hashimoto¹, Takeo Horie¹, Edwin Munro² (1. Graduate School of Frontier Biosciences, Osaka University, 2. Department of Molecular Genetics and Cell Biology, University of Chicago)

Closing Remarks(おわりに)