Symposium
Thu. Jul 18, 2024 9:00 AM - 11:30 AM Venue D (2F Conference Room 202)
Organizers:Takanari Inoue(Johns Hopkins University), Shiro Suetsugu(Nara Institute of Science and Technology)
Cell surface is never flat. It is rather a place enriched with various types of dents and bumps. The ones extending outward include microvilli, filopodia, blebs, spines, and cilia, to name a few. These cellular protrusions have been long thought to play a role in cell functions that require the sensation of environmental cues and/or generation of driving force to move forward. However, recent findings unexpectedly revealed their prevailing roles in cell-to-cell communications. For example, intercellular transfers of biomolecules are achieved through tunneling nanotubes of stem cells, as well as through extracellular vesicles released from cilia, microvilli, and filopodia of epithelial cells and fibroblasts. Collectively, cellular protrusions have to be revisited and redefined as structures responsible for dynamic cell-to-cell communications. In this symposium, we will broadly cover the latest exciting studies on a variety of cell protrusions and membrane structures, aiming to unravel their similarities and differences, and through this effort, we will naturally conclude what cellular protrusions are for in biology.
*Mayu Inaba1 (1. UConn Health, Department of Cell Biology)
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*Takanari Inoue1 (1. Johns Hopkins University)
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*Naokazu Inoue1 (1. Fukushima Medical Univ. School of Medicine)
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*Kenji Matsuzawa1 (1. Kyushu University Graduate School of Science)
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*Shiro Suetsugu1 (1. Nara Institute of Science and Technology)
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*Yuuta Imoto1, Kie Itoh1, Shigeki Watanabe2 (1. St.Jude Children's Research Hospital Department of Developmental Neurobiology, 2. Johns Hopkins University School of Medicine)
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*Takeshi Sawada1,2,3, Yusuke Iino3, Kensuke Yoshida3,4, Shinnosuke Nomura1,3, Hitoshi Okazaki1,2, Chika Shimizu3, Tomoki Arima1,2, Sho Yagishita1,2, Masashi Yanagisawa3, Taro Toyoizumi4, Haruo Kasai2, Shoi Shi3 (1. The University of Tokyo. Graduate School of Medicine, 2. The University of Tokyo. IRCN, 3. University of Tsukuba. IIIS, 4. RIKEN CBS)
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*Koji Ikegami1 (1. Grad Sch of Biomed & Health Sci, Hiroshima Univ)
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*Takanobu A Katoh1 (1. Dept. Cell Biol., Grad. Sch. Med., Univ. Tokyo)
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*KOJI ETO1 (1. Center for iPS Cell Research and Application, Kyoto University)
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