[1O-Ba] Oral Session 2

[1B10] Somatic epigenetic mosaicism of FDFT1 and clonal expansion of the FDFT1 epigenetically silenced cells underlies non-hereditary localized form of porokeratosis

*Akiharu Kubo^1,2, Sonoko Saito², Yuki Saito², Hisato Suzuki², Showbu Sato², Satomi Aoki², Masukazu Inoie⁴, Kenichiro Hata³, Keisuke Kataoka², Kenjiro Kosaki², Masayuki Amagai², Kazuhiko Nakabayashi³ (1. Kobe University, 2. Keio University School of Medicine, 3. National Center for Child Health and Development, 4. Japan Tissue Engineering Co., Ltd.)

Keywords:epimutation, cell competition, clonal expansion, mosaicism, mevalonate pathway