[29-413-am] Chemical biology 1

Fri. Mar 29, 2024 9:45 AM - 10:45 AM [Room 413] Conference Center 413 (4F)

Chair: Tanatani Aya, Masakazu Tanaka

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9:45 AM - 9:57 AM

[29-413-am01] Photo-chemical control of drug activity by novel photo-triggered cyclization reaction

○Hidenori Okamura^1,2, Arisa Kawamori^1,2, Momoka Iida^1,2, Yui Kaneyama^1,2, Mamiko Ozawa¹, Fumi Nagatsugi^1,2 (1. IMRAM, Tohoku Univ., 2. Grad. Sch. Sci., Tohoku Univ.)

9:57 AM - 10:09 AM

[29-413-am02S] Catalytic photo-oxygenation in liquid-liquid phase separation associated with tau aggregation

○Wataru Atsumi¹, Yuma Takeuchi¹, Shigehiro A Kawashima¹, Motomu Kanai¹ (1. Grad. Sch. Pharm. Sci., Univ. of Tokyo)

10:09 AM - 10:21 AM

[29-413-am03S] Development of Artificial Chromatin Writer enabling regioselective histone acetylation

○Mayu Onoda¹, Tamiko Nozaki¹, Yuma Takeuchi¹, Shigehiro Kawashima¹, Motomu Kanai¹ (1. Grad. Sch. Pharm. Sci., The Univ. of Tokyo)

10:21 AM - 10:33 AM

[29-413-am04S] Small Molecule Catalysts Function as Amyloid Breakers in vivo via Photooxygenation of Transthyretin Amyloids

○Mina Yamane¹, Hiroki Umeda¹, Moe Toyobe¹, Atsushi Iwai¹, Genki Kudo², Harunobu Mitsunuma^1,3, Yukiko Hori¹, Taisuke Tomita¹, Masamitsu Okada⁴, Mitsuharu Ueda⁴, Yukio Ando⁵, Takatsugu Hirokawa⁶, Shigehiro A. Kawashima¹, Youhei Sohma⁷, Kunitoshi Yamanaka⁸, Motomu Kanai¹ (1. Grad. Sch. Pharma. Sci., The Univ. Tokyo, 2. Appl. Sci., Grad. Sch. Sci. Tech., Univ. Tsukuba, 3. JST PRESTO, 4. Sch. Med., Kumamoto Univ., 5. Fac. Pharma. Sci., Nagasaki Int. Univ., 6. Faculty Med., Univ. Tsukuba, 7. Sch. Pharma. Sci., Wakayama Med. Univ., 8. IMEG, Kumamoto Univ.)

10:33 AM - 10:45 AM

[29-413-am05S] Drug discovery study on squarate covalent drugs targeting BRD4

○Hirokazu Takeshima¹, Yuri Takada¹, Yasunobu Yamashita¹, Yukihiro Ito¹, Takayoshi Suzuki¹ (1. SANKEN, Osaka Univ.)

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