Graduate and Undergraduate Student Symposium

[GS01] Observation, understanding, and application of "Symbiotic Weak Interaction" between Self and Non-self toward development of symbiotic materials

Fri. Mar 29, 2024 9:45 AM - 11:45 AM [Room 419] Conference Center 419 (4F)

Organizer: Shota Oyama (Grad. Sch. Biomed. Sci., Nagasaki Univ.), Haruka Takata (Grad. Sch. Pharm. Sci., Tokushima Univ.)

The immune system can distinguish 'self' from 'non-self' and eliminate the 'non-self' from the host. On the other hand, some 'non-self', such as the fetus and the intestinal bacteria, forms symbiotic relationship with the host and avoid elimination by the immune system. Although various functional biocompatible materials have been developed, the true "material symbiosis" has not been established.
In this symposium, we focus on the analysis of immune response against biological drugs and synthetic polymers such as polyethylene glycol, and the development of novel materials with immune tolerance or immune evasion. We will introduce six cutting-edge studies by graduate students and discuss the future perspectives in the symbiosis between materials and humans. We hope that this symposium will provide an opportunity for active discussions and a steppingstone for the development of 'symbiotic material'.

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オーガナイザー挨拶：大山将大（長崎大院医歯薬），髙田春風（徳島大薬院） (9:45 AM - 9:50 AM)

9:50 AM - 10:08 AM

[GS01-1] Production of DNA decoy only in tumor cells catalyzed by microRNA

○Soshu Yasuda¹, Kunihiko Morihiro¹, Akimitsu Okamoto¹ (1. Grad. Sch. Eng., Tokyo Univ.)

10:08 AM - 10:26 AM

[GS01-2] Development and functional evaluation of polysaccharide derivatives exhibiting anti-inflammatory action

○Aino Komoda¹, Yukiya Kitayama¹, Eiji Yuba¹, Atsushi Harada¹ (1. Grad. Sch. Eng., Osaka Metropolitan Univ.)

10:26 AM - 10:44 AM

[GS01-3] Encapsulation of an antioxidant in redox-sensitive albumin nanoparticles

○Kengo Yasuda¹, Hitoshi Maeda¹, Ryo Kinoshita¹, Yuki Minayoshi¹, Yuki Mizuta¹, Yuka Nakamura¹, Shuhei Imoto², Koji Nishi², Keishi Yamasaki², Mina Sakuragi³, Teruya Nakamura¹, Mayumi Ikeda⁴, Yasunori Iwao⁴, Yu Ishima⁵, Tatsuhiro Ishida⁶, Yasuko Iwakiri⁷, Masaki Otagiri², Hiroshi Watanabe¹, Toru Maruyama¹ (1. Grad. Sch. Pharm. Sci., Kumamoto Univ., 2. Fac. Pharm. Sci., Sojo Univ., 3. Fac. Eng., Sojo Univ., 4. Sch. Pharm. Sci., Wakayama Med. Univ., 5. Kyoto Pharm. Univ., 6. Inst. Biomed. Sci., Tokushima Univ., 7. Yale Univ. Sch. Med.)

10:44 AM - 11:02 AM

[GS01-4] Understanding and control of interaction between acyclic artificial nucleic acids and biomolecules

○Kiyoka Sakashita¹, Masaya Higuchi¹, Yukiko Kamiya², Hiroyuki Asanuma¹ (1. Grad. Sch. Eng. Sci., Nagoya. Univ., 2. Kobe Pharm. Univ.)

11:02 AM - 11:20 AM

[GS01-5] Safe and efficient oral allergy immunotherapy using mannan-coated allergen nanoparticles

○Takanatsu Hosokawa¹, Shunyi Li¹, Hiroki Toriumi², Daisuke Takahashi², Tomoko Kamasaki³, Yoichiro Fujioka³, Satoru Nagatoishi⁴, Jinting Li¹, Yiwei Liu⁵, Kouhei Tsumoto⁴, Yusuke Ohba³, Yoshiki Katayama^1,5, Daisuke Murakami⁶, Koji Hase², Takeshi Mori^1,5 (1. Grad. Sch. Sys. Life. Sci., Kyushu Univ., 2. Grad. Sch. Pharm. Sci., Keio Univ., 3. Grad. Sch. Med., Hokkaido Univ., 4. Inst. Med. Sci., UTokyo, 5. Fac. Eng., Kyushu Univ., 6. Grad. Sch. Med. Sci., Kyushu Univ.)

11:20 AM - 11:38 AM

[GS01-6] Impact of administration route of PEGylated liposomes on the induction of anti-PEG antibodies

○Rina Yamade^1,2, Haruka Takata^1,2, Hidenori Ando^1,2, Tatsuhiro Ishida^1,2 (1. Grad. Sch. Pharm. Sci., Tokushima Univ., 2. Institute of innovative DDS, Tokushima Univ.)

総括：大山将大（長崎大院医歯薬），髙田春風（徳島大薬院） (11:38 AM - 11:45 AM)

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