[29P-pm094S] Application of Graft-type polymer with immobilized catalyst using microwave to flow reaction

Yoshinori Okuno¹, ○Arisa Sera¹, Ayu Kobayashi¹, Shunsuke Tenma¹, Takuya Iwamura¹, Yasuyo Mitsutaki¹, Kento Sekizuka¹, Nami Kawasaki¹, Ran Higashisanjo¹, Toshiyasu Nakakita¹, Syoji Aoki², Shigeki Isomura¹, Yasuo Sato¹ (1. Yokohama University of Pharmacy, 2. ECE Co., Ltd.)

[29P-pm095] Identification of 2-(difluoroanilino)-chromen-4-one analogues with tumoricidal effects on multidrug-resistant cancers

○YI-Han Chang^1,2, I-Ting Wu³, Chin-Chuan Hung³, Hsin-Yi Hung² (1. Institute of Chemistry, Academia Sinica, Taipei, Taiwan, 2. School of Pharmacy, College of Medicine, National Cheng Kung University, Tainan, Taiwan , 3. Department of Pharmacy, College of Pharmacy, China Medical University, Taichung, Taiwan)

[29P-pm096] Eperisone analogues as a rescuer of mistranslation by CDKAL1 defect; synthesis and antihyperglycemic effect.

Manabu Tejima¹, Tomoko Hashimoto¹, Mana Nakagawa¹, Tomoyuki Hoshina¹, Osamu Ohno¹, Kotaro Takasaki², Shintaro Taniguchi², Kanako Nakamura², Ayano Goto², Chiaki Yonebara², Fan-Yan Wei³, Kazuhito Tomizawa⁴, ○Kenji Matsuno⁵ (1. Sch. Adv. Engin., Kogakuin Univ., 2. Fac. Pharm. Sci., Teikyo Heisei Univ., 3. Grad. Sch. Life Sci., Tohoku Univ., 4. Fac. Life Sci., Kumamoto Univ., 5. Fac. Pharmacy, Yasuda Women's Univ.)

[29P-pm097] Characterization of direct target proteins in the cytoplasm of ST32da, an ATF3-induced single compound

○Nain Chu Gao¹, Wei-Jan Huang¹, Heng Lin² (1. Graduate Institute of Pharmacognosy, College of Pharmacy, Taipei Medical University, Taipei, Taiwan, 2. Department of Physiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan)

[29P-pm098] Drug discovery research of naphthoquinone derivatives for the treatment of Onychomycosis

○Yoshihiko Noguchi^1,2, Naoaki Arima³, Kazunari Sakai³, Kazutoyo Abe³, Ken Sasaki², Tadaaki Ohgiya³, Tomoyasu Hirose^1,2, Toshiaki Sunazuka^1,2, Hideaki Hanaki^1,2 (1. Grad. Sch. Infect. Ctl. Sci., Kitasato Univ., 2. Ōmura Satoshi Memorial Insti., Kitasato Univ., 3. Kowa company, LTD.)

[29P-pm099] Indole-2-carboxamide derivatives with enhanced antibacterial activity against nontuberculous mycobacteria and improved water solubility

○Atsushi Seki¹, Isao Momose¹, Chigusa Hayashi¹, Masayuki Igarashi¹, Masakatsu Shibasaki¹ (1. Inst. of Microb. Chem.)

[29P-pm100] Development and application of "VED" to heal itching caused by atopic dermatitis, pain, scars, cramps, skin spots, acne scars, muscle pain, etc.

○Masanori Somei¹, Hiizu Somei¹, Kazuko Somei¹ (1. SOMEIYAKKO Kenkyusho)

[29P-pm101] The omega-9 monounsaturated fatty acid in Sapindus mukorossi seed prevent periodontitis in animal model with ligature-induced periodontitis

○Haw-Ming Huang¹, Shih-Kai Lin¹, Li-Fu Chen¹ (1. Sch. Dent., Taipei Med. Univ. Taipei, Taiwan)

[29P-pm102S] Synthetic Study of JBIR-155, a Specific Class D β-lactamase Inhibitor

○Yoshiki Yoshida¹, Takehiro Nishimura¹, Haruhisa Kikuchi¹ (1. Fac. Pharm., Keio Univ.)

[29P-pm103] The treatment efficiency of Sapindus mukorossi seed hydrosol on the periodontitis: A microbiome analysis

○Li-Fu Chen¹, Xiang-Wei Chen¹, Shih-Kai Lin¹, Haw-Ming Huang¹ (1. Sch. Dent., Taipei Med. Univ. Taipei, Taiwan)

[29P-pm104] Anti-bacterial, anti-inflammatory and skin regeneration effects of Sapindus mukorossi seed water extract

○Hsuan-Yu Lai¹, Haw-Ming Huang¹ (1. Sch. Dent., Taipei Med. Univ.)

[29P-pm105S] Dissolution of cannabidiol in hydrated ionic liquids for skin permeation application

○Mineto Koyanagi¹, Ruriko Kawanabe², Ayumu Yoshizaki², Kyoko Fujita¹ (1. School of Pharmacy Tokyo University of Pharmacy and Life Sciences, 2. Graduate School of Medicine and Faculty of Medicine, The University of Tokyo)

[29P-pm106S] Analysis of the interaction between DNA aptamers and target molecules in hydrated ionic liquids

○Hidenori Tsukuhiji¹, Shintaro Inaba², Takuya Honda², Kaori Tsukakoshi², Hiroyuki Ohno², Kazunori Ikebukuro², Kyoko Fujita¹ (1. School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 2. Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology)

[29P-pm107] Effects by N-substituted N-demethylsinomenine on inhibitory effects against acute nociceptive response induced by formalin on mice

○Hiroki Kataoka¹, Soh Katsuyama¹, Yukino Ogasawara¹, Naoko Okada¹, Toshiaki Saitoh¹, Fumihide Takano¹, Chikai Sakurada¹ (1. Nihon Pharm. Univ.)

[29P-pm108S] Synthesis of antitrypanosomal compounds based on lignan lactone skeletons

○Yuka Tani¹, Takehiro Nishimura¹, Haruhisa Kikuchi¹ (1. Fac. Pharm., Keio Univ.)

[29P-pm109] Structural design of negative pressure-driven pharmaceutical nebulizer: A computational fluid dynamics analysis

○Hung-Chieh Wu¹, Haw-Ming Huang¹ (1. Sch. Dent., Taipei Med. Univ.)

[29P-pm110] CFD Study of the Effect of the Angle Pattern on Iliac Vein Compression Syndrome

○Hsuam Wei Chen¹, Haw-Ming Huang² (1. Graduate Institute of Biomedical Materials and Tissue Engineering, Taipei Medical Univ., 2. School of Dentistry, Taipei Medical University, Taiwan)

[29P-pm111] Development of the bicyclic mid-size peptide KS-133 as a VIPR2-specific antagonist and its antitumor effect through modulation of macrophage polarity

○Kotaro Sakamoto¹, Eijiro Miyako², Shinsaku Nakagawa³, Yukio Ago⁴, Akira Nishiyama⁵ (1. Ichimaru Pharcos co. Ltd., 2. JAIST, 3. Osaka Univ., 4. Hiroshima Univ., 5. Kagawa Univ.)

[29P-pm112] Purity Confirmation of Synthetic Peptides - Amino Acid Analyses -

○Tomoko Kuriki¹, Ayano Tanabe¹, Hidetoshi Terada¹ (1. SHIMADZU CORPORATION)

[29P-pm113] Amino acid sequence analysis of synthetic peptides using protein sequencer

○Miho Akagi¹, Ryo Nagano¹, Ayaka Hori¹, Kumiko Yamaguchi¹, Tomoko Kuriki¹, Hidetoshi Terada¹ (1. SHIMADZU CORPORATION)

[29P-pm114] Determination for the Molecular Weight of Synthetic Peptides by single quadrupole mass spectrometer

○Miho Kawashima¹, Tomoko Kuriki¹ (1. Shimadzu Corporation)

[29P-pm115] Streamlining of Synthetic Peptides Purification Using Analytical-Preparative Switching LC-MS System

○Yusuke Masuda¹, Yuki Suzuki¹, Tomoko Kuriki¹, Ryo Kubota¹, Hidetoshi Terada¹ (1. Shimadzu Corporation)

[29P-pm116] Purity Confirmation of Synthetic Peptides - Determination of Counter Ions -

○Ayano Tanabe¹, Tomoko Kuriki¹, Hidetoshi Terada¹ (1. Shimadzu Corporation)

[29P-pm117S] Synthesis of middle-molecules from abietic acid using a natural product reconstruction strategy

○Fumiaki Kobayashi¹, Takehiro Nishimura¹, Haruhisa Kikuchi¹ (1. Fac. Pharm., Keio Univ.)

[29P-pm118] Construction of HUVEC and HL-60 cell adhesion activity assay and inhibitory effect of SLeX-related product

○Susumu Kawano¹, Kaisei Motoyama¹, Yuka Shirahama¹, Eito Okamoto¹, Hiroaki Kaji¹ (1. Shujitsu University School of Pharmacy)

[29P-pm119S] Identification of specific substrate peptides for the detection of MMP-12 activity

○Ryuta Maruoka¹, Sota Yamada^1,2, Eita Sasaki^1,2, Kotaro Matsumoto³, Masaru Takeshita³, Kenjiro Hanaoka^1,2 (1. Fac. Pharm., Keio Univ, 2. Grad. Sch. Pharm. Sci., Keio Univ., 3. Fac. Med.,Keio Univ)

[29P-pm120S] Study on the synthesis of heterobivalent compounds composed of oxytocin and endomorphin-1 aimed for a novel bitopic ligand for mu-opioid receptor

○Takeru Chiba¹, Takaaki Mizuguchi¹, Hideaki Fujii¹ (1. Kitasato University, School of Pharmacy)

Session information

[29P-pm] Synthetic compounds in drug discovery/Natural medicines and biological products/Middle-molecule drugs