Session information

Oral Presentation

(E) Pharmaceutical Health Care and Sciences

[30-313-am] Metabolism/Drug interaction

Sat. Mar 30, 2024 8:30 AM - 9:30 AM [Room 313] Conference Center 313+314 (3F)

Chair: Toshiyuki Kudo, Junya Nagai

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8:30 AM - 8:42 AM

[30-313-am01S] Safety evaluation of adeno-associated virus vectors using human liver models

○Yoshitaka Nakata¹, Ryosuke Negoro², Sayaka Deguchi¹, Yakuya Yamamoto¹, Kazuo Takayama¹ (1. CiRA, Kyoto Univ., 2. Dept. of Pharm. Sci., Ritsumeikan Univ)

8:42 AM - 8:54 AM

[30-313-am02S] Mechanisms of attenuation of phenobarbital-induced cytochrome P450 expression in mice model with hepatitis

○Yukine Kubo¹, Chieri Fujino¹, Satoshi Ueshima¹, Toshiya Katsura¹ (1. College of Pharm. Sci., Ritsumeikan Univ.)

8:54 AM - 9:06 AM

[30-313-am03] Acetaminophen hepatotoxicity induced via the circulatory system : Interaction between cytochrome P450 metabolites and red blood cells

○Yukari Ueda¹, Tadatoshi Tanino¹, Yuka Ishihara¹, Minori Saijo¹ (1. Tokushima Bunri University, Faculty of Pharmaceutical Sciences)

9:06 AM - 9:18 AM

[30-313-am04] A New Model to Comprehensively Explain Atypical CYP3A Metabolic Reactions with One Substrate Recognition Site: Big Site Model

○Yuta Tamemoto¹, Natsumi Hashimoto¹, Hana Kumemura¹, Keita Takahashi¹, Hiromi Sato¹, Akihiro Hisaka¹ (1. Grad. Sch. Pharm. Sci., Chiba Univ.)

9:18 AM - 9:30 AM

[30-313-am05] CYP3A- and MDR1-mediated drug-drug interaction in humanized mice in vivo

○Genki Minegishi¹, Satoshi Abe^2,3, Kanako Kazuki^2,3, Naoyo Kajitani^2,3, Atsushi Miyajima¹, Yasuhiro Kazuki^2,3, Kaoru Kobayashi¹ (1. Meiji Pharm. Univ., 2. Grad. Sch. of Med., Tottori Univ., 3. Chrom. Engn. Res. Ctr., Tottori Univ.)