[30-413-pm] Chemical biology 3

Sat. Mar 30, 2024 3:30 PM - 4:30 PM [Room 413] Conference Center 413 (4F)

Chair: Naoya Shindo, Masafumi Tamura

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3:30 PM - 3:42 PM

[30-413-pm11S] Mechanistic study of transcriptional activation by artificial histone acetylation catalysis

○Shinpei Takamaru¹, Yuki Yamanashi¹, Shigehiro Kawashima¹, Motomu Kanai¹ (1. Grad. Sch. Pharm. Sci., University of Tokyo)

3:42 PM - 3:54 PM

[30-413-pm12S] The development of a photoregulatable lysine acetylation catalyst towards generating an oscillation of histone acetylation.

○Yuto Azumaya¹, Yugo Kamimura¹, Tatsushi Yabuta², Hayu Hasebe², Mie Fuyama², Kenzo Yamatsugu¹, Shigehiro A Kawashima¹, Yuki Yamanashi¹, Ryosuke Matsubara², Motomu Kanai¹ (1. Grad. Sch. Pharm., The Univ. of Tokyo, 2. Grad. Sch. Sci., Kobe Univ.)

3:54 PM - 4:06 PM

[30-413-pm13S] Multivalent Chromatin Binding Promotes Transition to Solid-like Chromatin

○Shuhei Terada¹, Yugo R Kamimura¹, Shigehiro A Kawashima¹, Motomu Kanai¹ (1. Grad. Sch. Pharm. Sci., Univ. of Tokyo)

4:06 PM - 4:18 PM

[30-413-pm14S] Development of chemical probes for the exploration of anti-tumor targets of bicyclic depsipeptides constrained by bridge bonds

○Hatuki Yamada¹, Mieko tsuji¹, Tasuku Hirayama¹, Hideko Nagasawa¹ (1. Gifu Pharmaceutical University)

4:18 PM - 4:30 PM

[30-413-pm15] Elucidation of the structure-activity relationship of nuclear-localized porphyrins for application as a new photodynamic therapy against cancer

○Toshifumi Tojo¹, Natsumi Hayakawa², Takeshi Kondo^2,3, Shin Aoki^1,3, Makoto Yuasa^2,3 (1. Grad. Sch. Pharm. Sci., Tokyo Univ. of Sci., 2. Grad. Sch. Sci. Technol., Tokyo Univ. of Sci., 3. Res. Inst. Sci. Tech., Tokyo Univ. of Sci.)

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