[30P-am462] Construction of a rat model for renal interstitial fibrosis by tacrolimus administration following 5/6 nephrectomy.

○Yuko Nakayama¹, Sachiko Kamikawa¹, Daichi Nakajima¹, Taketo Miki¹, Akari Narita¹, Satohiro Masuda¹ (1. Facul. Pharm. Sci., Himeji Dokkyo Univ.)

[30P-am463] Phenotypic differences depending on genetic background in glial calcineurin-knockout mice in which small intestine inflammation is induced

Takaki Yagi¹, Hana Tatsuno¹, Kana Suzaki¹, Naohide Hirashima¹, ○Masahiko Tanaka¹ (1. Grad. Sch. Pharm. Sci., Nagoya City Univ.)

[30P-am464S] Morphological analysis of iPS-derived neurons from patients with Lesch-Nyhan Syndrome

○Yudai Sato¹, Natsuki Oyake¹, Mai Sekine¹, Makoto Hosoyamada², Kimiyoshi Ichida³ (1. Tokyo University of Pharmacy and Life Sciences, 2. Teikyo univ., 3. JR East Health Promotion Center)

[30P-am465S] Investigation of a new animal model of aspiration pneumonia in mice by combining repeated administration of hydrochloric acid with a single low dose of LPS.

○Runa Koizumi¹, Yasuhisa Izushi¹, Yoshihisa Kitamura¹, Yuichi Tasaka¹ (1. Sch. Pharm., Shujitsu Univ.)

[30P-am466] The relationship between TNF receptor subtypes and the development of insulin resistance

○Yoko S Kaneko¹ (1. Dept. of Pharm., Gifu Univ. of Med. Sci.)

[30P-am467] The influence of chronic kidney disease through changes gut microbiota via fed a high-protein diet

○Takafumi Seo¹, Chiho Takahara¹, Kento Takayama¹ (1. Kampo Pharm. Sci., Fukuyama Univ.)

[30P-am468S] Detection of atherosclerotic lesions using radioisotope-labeled oxidized LDL in mice

○Yui Okuno¹, Hidekazu Kawashima², Michi Izawa¹, Jyunna Nakaya¹, Mayuko Takeda¹, Keiichi Ishihra³, Satoshi Akiba³, Kazuyuki Takata¹ (1. Jnt. Res. Lab., 2. Radioisotope Res. Cent., Kyoto Pharm. Univ., 3. Dept. Pathol. Biochem., Kyoto Pharm. Univ.)

[30P-am469] Methionine kinetics in 5/6-nephrectomized rats with diet-induced hyperhomocysteinemia

○Yoshiki Sawada¹, Yuka Tamura¹, Kazue Matsuo¹, Sayaka Iizuka¹, Mokana Tamura¹, Yuna Hashimoto¹, Shoma Iritani¹, Yumiko Matsuyama¹, Kimiyoshi Ichida¹, Yoshihiko Shinohara¹, Hiroshi Hasegawa¹ (1. Tokyo Univ Pharm and Life Sci)

[30P-am470] Analysis for sex differences in bile secretion

○yamazaki yasuhiro^1,2, hasegawa yui², kurokawa junko² (1. Shonan Univ. Med. Sci., 2. Sch. Pharm. Sci. Univ. of Shizuoka)

[30P-am471S] Possible involvement of zinc transporter ZIP13 in myogenic differentiation: Study using iPSCs from patients with Ehlers–Danlos syndrome spondylodysplastic type 3

○Saki Nagase¹, Masaki Shoji¹, Haato Yuri¹, Takuto Ohashi², Takafumi Hara², Emi Yoshigai², Ayako Fukunaka³, Yoshio Fujitani³, Hidetoshi Sakurai⁴, Heloísa G. dos Santos⁵, Toshiyuki Fukada², Takashi Kuzuhara¹ (1. Lab. Biochem., Facul. Pharm. Sci., Tokushima Bunri Univ., 2. Dep. Mol. Cell. Physiol., Facul. Pharm. Sci., Tokushima Bunri Univ., 3. Lab. Dev. Biol. Metab., Ins. Mol.Cell. Reg., Gunma Univ., 4. Dep.Clin. Appl. CiRA., Kyoto Univ., 5. Serviço Genética Médica, Hosp. S. Maria.)

[30P-am472] Efficacy of lacosamide and perampanel on social interaction in autism spectrum disorder model mice

○Yuka Moriya¹, Fuyuka Ito¹, Mai Miyachi¹, Satomi Matsuoka¹, Takemi Fuwa², Hitomi Kurahashi², Akihiro Mouri², Yoichi Hasegawa¹ (1. Faculty of Pharmacy, Meijo Univ., 2. Fujita Health Univ.)

[30P-am473S] Analysis of changes in serum amyloid A expression associated with lipid droplet accumulation

○Masaki Shimada¹, Toru Takarada¹, Masakazu Fukuda¹, Masafumi Tanaka¹ (1. Kobe.Pharm.Univ.)

[30P-am474S] Alleviation of Abnormal Glucose Metabolism in Alzheimer's Disease Mouse Model by Endothelial Cell Senescence

○Natsuka Yamada¹, Sayo Horibe¹, Taeko Kitano¹, Yuka Tsuchihashi¹, Risa Takenaka¹, Toru Tanaka¹, Shoji Kawauchi¹, Naoto Sasaki¹, Koji Ikeda^1,2, Noriaki Emoto¹, Ken-Ichi Hirata³, Yoshiyuki Rikitake¹ (1. Kobe pharmaceutical Univ., 2. Grad. Sch. Med., Kyoto pref. Univ., 3. Grad. Sch. Med.,Kobe. Univ.)

[30P-am475S] The study of therapeutic strategy against steatohepatitis caused by Atp8b1 knockout in intestinal epithelial cells

○Haruki Kitazato¹, Ryutaro Tamura¹, Yusuke Sabu¹, Hiroyuki Kusuhara¹, Hisamitsu Hayashi¹ (1. Grad. Sch. Pharm. Sci., Tokyo Univ.)

[30P-am476] Sexually dimorphic mechanism of migraine chronification

○Daigo Ikegami^1,2, Edita Navratilova², Xu Yue², Caroline M Kopruszinski², Masahiko Funada¹, Frank Porreca² (1. Shonan Univ. Med. Sci., 2. Univ. Arizona)

[30P-am477] Analysis of circadian rhythms in corticosterone-treated mice

○Hiroshi Kawai¹, Koki Takeda¹, Reiko Iwadate¹ (1. Laboratory of Health Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Josai University)

Session information

[30P-am] Pathophysiology