[31-313-pm] Genetic drug delivery system 2

Sun. Mar 31, 2024 1:15 PM - 2:15 PM [Room 313] Conference Center 313+314 (3F)

Chair: Higuchi Yuriko, Suzuki Takahiro

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1:15 PM - 1:27 PM

[31-313-pm01S] Development of bile acid-modified mRNA-encapsulated lipid nanoparticles for improved uptake into intestinal epithelial cells after oral administration

○Toma Shinkai¹, Koki Ogawa¹, Tatsuaki Tagami¹, Tetsuya Ozeki¹ (1. Grad. Sch. Pharm. Sci., Nagoya City Univ.)

1:27 PM - 1:39 PM

[31-313-pm02S] Effect of ionizable lipids on pH-dependent structured changes of lipid nanoparticles

○Yui Sakagawa¹, Keisuke Ueda¹, Kenjirou Higashi¹, Kunikazu Moribe¹ (1. Faculty of Pharmaceutical Sciences, Chiba University)

1:39 PM - 1:51 PM

[31-313-pm03S] Effect of polymer/ peptide assembled nanoparticle size on gene expression in the brain stem and spinal cord after nasal administration.

○Shunsuke Aoki¹, Takanori Kanazawa^1,2, Shingo Iioka¹, Hiromu Kondo¹ (1. Grad. Sch. Pharm. Sci., Univ of Shizuoka, 2. Grad. Sch. Biomed Sci., Tokushima Univ)

1:51 PM - 2:03 PM

[31-313-pm04S] Knockdown activity of oligonucleotide-loaded peptide/block copolymer assembled nanoparticles in brain and spinal cord after nasal administration.

○Shingo Iioka¹, Takanori Kanazawa^1,2, Hiromu Kondo¹ (1. Grad. Sch. Pharm. Sci., Univ. of Shizuoka., 2. Grad. Sch. Biomed. Sci., Tokushima Univ.)

2:03 PM - 2:15 PM

[31-313-pm05S] siRNA-loaded multifunctional peptide-modified liposomes for eyedrop: siRNA delivery to the retina and suppressive effect of VEGF production

○Anju Hasegawa¹, Yuuki Takashima¹, Shogo Nishida¹, Aoi Nosaka¹, Kaho Endo¹, Hiroshi Ishihara¹ (1. Tokyo Univ.of Pharmacy and Life Sciences)

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