[31-511-pm] Other synthetic studies

Sun. Mar 31, 2024 2:15 PM - 3:15 PM [Room 511] Conference Center 511+512 (5F)

Chair: Eiko Yasui, Daisuke Yamamoto

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2:15 PM - 2:27 PM

[31-511-pm06] Selective modification of tryptophan in polypeptides via oxidative coupling using in-situ-generated hypervalent iodine species in acidic aqueous media

○Kengo Hanaya¹, Shunsuke Watanabe¹, Yuki Wada², Masaki Kawano², Shuhei Higashibayashi¹, Takeshi Sugai¹ (1. Faculty of Pharmacy, Keio University, 2. Department of Chemistry, Tokyo Institute of Technology)

2:27 PM - 2:39 PM

[31-511-pm07S] Direct synthesis of peptide alkyl hydrazides using dialkoxybenzyl-type linker and its application to ubiquitin synthesis

○Takaya Yamamoto¹, Tetsuo Narumi¹, Nobuyuki Mase¹, Kohei Sato¹ (1. Graduate School of Integrated Science and Technology, Shizuoka University)

2:39 PM - 2:51 PM

[31-511-pm08S] SARS-CoV-2 drug research using peptides with unnatural amino acids

○Yusaku Honda¹, Yunosuke Koga¹, Suyong Re², Kenji Mizuguchi^2,3, Daisuke Takahashi¹, Ryo Yazaki¹, Takashi Ohshima¹ (1. Kyushu Univ., 2. NIBIOHN, 3. Osaka Univ.)

2:51 PM - 3:03 PM

[31-511-pm09S] Bioactivity modulation of gramicidin A by substitution of Trp with its positional isomers

○Takahiro Migita¹, Hiroaki Itoh¹, Masayuki Inoue¹ (1. Grad. Sch. Pharm. Sci., U. Tokyo)

3:03 PM - 3:15 PM

[31-511-pm10] Green diastereospecific synthesis of various medicine analogues containing dipeptides and release of the medicines by Baker’s yeast

○Shin Satoh¹, Sunghee Jung^1,2, Hideyuki Daitoku¹, Takuya Noguchi¹, Yuya Kawashima¹, Nobuyuki Imai¹ (1. Department of Pharmacy, Chiba Institute of Science, 2. Seogwipo Medical Center, Jeju Province)

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