Discovery of hydrophobic pockets near the GAA active site and creation of selective chaperone compounds against Pompe disease.

○Atsushi Kato

[30P-pm094] Discovery of hydrophobic pockets near the GAA active site and creation of selective chaperone compounds against Pompe disease.

○Atsushi Kato¹, Izumi Nakagome², Maki Kise¹, Kousuke Yoshimura¹, Takuya Okada³, Naoki Toyooka³, Nobutada Tanaka² (1. Department of Hospital Pharmacy, University of Toyama, 2. School of Pharmaceutical Sciences, Kitasato University , 3. Graduate School of Science and Engineering, University of Toyama)

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Presentation information

[30P-pm] Drug design/Screening/adioisotopes, radiopharmaceuticals/Others

[30P-pm094] Discovery of hydrophobic pockets near the GAA active site and creation of selective chaperone compounds against Pompe disease.

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