Conversion of anti-TNFR2 biparatopic antibody from agonist to antagonist by structural modification.

○Takuya Otsuki

Presentation information

Oral Presentation

(A) Pharmaceutical Chemistry

[31-413-am] Modalities, biomolecules, biologics

Sun. Mar 31, 2024 9:45 AM - 10:45 AM [Room 413] Conference Center 413 (4F)

Chair: Yukihiro Itoh, Satoshi Ichikawa

9:57 AM - 10:09 AM

[31-413-am07S] Conversion of anti-TNFR2 biparatopic antibody from agonist to antagonist by structural modification.

○Takuya Otsuki¹, Hiroki Akiba^1,2, Junso Fujita^3,4, Keiichi Namba^3,4, Haruhiko Kamada^1,2, Hiroaki Ohno^1,2 (1. Grad. Sch. Pharm. Sci., Kyoto Univ., 2. NIBIOHN, 3. Grad. Sch. Front. Biosci., Osaka Univ., 4. JEOL YOKOGUSHI Res. Alliance Lab., Osaka Univ.)

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Presentation information

[31-413-am] Modalities, biomolecules, biologics

[31-413-am07S] Conversion of anti-TNFR2 biparatopic antibody from agonist to antagonist by structural modification.

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