[1P0171] Bone marrow producing osteopontin supports hematopoietic stem/progenitor cells through CD44

〇Masaya Yano¹, Azusa Imanishi¹, Leo Matsubara¹, Akio Maekawa¹, Satowa Tanaka¹, Hiroki Nagasaki¹, Asami Kawai¹, Natsumi Hasegawa¹, Shigetaka Asano^2,3, Mitsuhiro Ito^1,2,4 (1.Division of Medical Biophysics, Kobe University Graduate School of Health Sciences, Kobe, 2.Waseda University Research Organization for Nano & Life Innovation, Tokyo, 3.Division of System Biology of Disease, Kobe University Graduate School of Medicine, 4. Laboratory of Biochemistry and Molecular Biology, the Rockefeller University)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P0172] Pannexin 3 is a new regulator that inhibits osteoprogenitor proliferation and susquently promotes differentiation to osteoblasts

〇Masaki Ishikawa^1,2, Geneva L. Williams², Satoshi Fukumoto³, Yoshihiko Yamada² (1.Dept. of Rest. Dent., Div. of Opera. Dent., Grad. Sch. of Dent., Univ. of Tohoku, 2.LCDB.,NIDCR,NIH, 3.Dept. of Pediatric. Dent., Grad. Sch. of Dent., Univ. of Tohoku)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P0173] Ki16425, a selective lysophosphatidic acid receptor of LPA1-3, radiosensitizes pancreatic cancer cells.

〇Mayumi Komachi¹, Shin-ei Noda^1,2, Kota Torikai², Kazutoshi Murata², Nobuteru Kubo¹, Takashi Nakano^1,2 (1.Dept. of Rad Onc., Grad. Sch. of Med., Gunma Univ, 2.Gunma Univ. Heavy Ion Med Center)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P0174] Spermidine and Ca2+, but not Na+, can permeate NMDA receptors in the presence of Mg2+

Tadao Hirose¹, 〇Kyohei Higashi¹, Ryotaro Saiki^1,2, Yuki Yoshizawa¹, Masataka Imamura¹, Itsuko Ishii¹, Toshihiko Toida¹, Keith Williams³, Keiko Kashiwagi⁴, Kazuei Igarashi^1,2 (1.Grad. Sch. of Pharm. Sci., Chiba Univ., 2.Amine Pharma Res. Inst., 3.State Univ. of New York Downstate Medical Center, 4.Fac. of Pharm., Chiba Inst. of Sci.)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P0175] Enzymatic production of polysulfides and their function of activating TRPA1 channels in rat brain

〇Yuka Kimura¹, Yoshinori Mikami², Kimiko Osumi¹, Mamiko Tsugane³, Jun-ichiro Oka⁴, Yukiko Toyofuku¹, Shin Koike^1,5, Norihiro Shibuya¹, Noriyuki Nagahara⁶, Yuki Ogasawara⁵, Hideo Kimura¹ (1.Dept. of Mol. Pharmacol., Natl. Inst. Neurosci., NCNP, 2.Dept. of Cell. Mol. Pharmacol., Grad. Sch. Med., Univ. of Tokyo, 3.Fcalty. Sci., Eng., Chuo Univ., 4.Dept. Pharmacy, Tokyo Univ. of Sci., 5.Dept. Anal. Biochem, Meiji Pharm. Univ., 6.Radioisotope center, Nippon Med. Sch.)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P0176] Development of site-specific labeling technique toward functional analysis of cell surface receptors

〇Sae Ichii¹, Makiko Neyazaki¹, Rika Oi¹, Takeshi Sato², Terukazu Nogi¹ (1.Grad.Sch. of Med.Lif.Sci. Yokohama City Univ., 2.Inst. for Prot.Res. Osaka Univ.)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P0177] Characterization of proton-sensing GPR4 selective modulators in extracellular acidification-induced responses

〇Ayaka Tobo¹, Koichi Sato¹, Masayuki Tobo¹, Chihiro Mogi¹, Fumikazu Okajima¹ (1.Lab. of Signal Transduct.,IMCR,Gunma Univ.)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P0178] Effect of polyamines on histamine biosynthesis in bone marrow derived mast cells.

〇Toshio Mizuta¹, Kazuhiro Nisimura¹, Tohru Shibayama¹, Satoshi Tanaka², Toshihiko Toida¹, Kazuei Igarashi^1,3 (1.Grad. Sch. Pharm. Sci., Chiba Univ., 2.Grad. Sch. of Med., Dent., and Pharm. Sci., Okayama Univ., 3.Amine Pharma Res. Inst.)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P0179] Effect of AGEs on cellular responses induced by cytokine which interacts with HMGB1

〇Masahiro Watanabe¹, Takao Toyomura¹, Hidenori Wake², Keyue Liu², Kiyoshi Teshigawara², Hideo Takahashi³, Masahiro Nishibori², Shuji Mori¹ (1.Sch. of Pharm., Shujitsu Univ., 2.Grad. Sch. of Med., Dent. and Pharm. Sci., Okayama Univ., 3.Fac. of Med., Kinki Univ.)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM

[1P0180] Search of HMGB1-binding factor with the activity enhancing AGEs-RAGE binding

〇Shuji Mori¹, Masahiro Watanabe¹, Hidenori Wake², Keyue Liu², Kiyoshi Teshigawara², Hideo Takahashi³, Masahiro Nishibori², Takao Toyomura¹ (1.Sch Pharm, Shujitsu Univ, 2.Grad Sch Med Dent Pharm Sci, Okayama Univ, 3.Fac Med, Kinki Univ)

BMB2015 Biochemistry and Molecular Biology |Tue. Dec 1, 2015 4:45 PM - 6:45 PM