[3P1081(4T18L-04)] Genetic analysis of tumor progression triggered by intratumor heterogeneity

〇Takao Ito¹, Masato Enomoto¹, Tatsushi Igaki^1,2 (1.Lab of Genet., Grad. Sch. of Bio., Kyoto Univ., 2.JST, PRESTO)

BMB2015 Biochemistry and Molecular Biology |Thu. Dec 3, 2015 4:45 PM - 6:45 PM

[3P1082(4T18L-05)] Nrf2 promotes a transition from steatohepatitis to liver cancer in Pten deficiency

〇Keiko Taguchi¹, Risa Ichinohe¹, Masayuki Yamamoto¹ (1.Dept. of Med. Biochem., Grad. Sch. of Med., Tohoku Univ.)

BMB2015 Biochemistry and Molecular Biology |Thu. Dec 3, 2015 4:45 PM - 6:45 PM

[3P1084(4T18L-07)] Development of new diagnostic biomarkers for the early-stage breast cancer patient based on autoantibody in serum.

〇Sayaka Matsumoto¹, Hiroyuki Takeda¹, Yohei Miyagi², Tatsuya Sawasaki¹ (1.PROS, Ehime Univ., 2.Kanagawa Cancer Center Research Institute)

BMB2015 Biochemistry and Molecular Biology |Thu. Dec 3, 2015 4:45 PM - 6:45 PM

[3P1085(4T18L-08)] The metabolic function of RB in controlling mevalonate (MVA) pathway regulates tumor progression through antioxidant activity

〇Nobunari Sasaki^1,2, Misa Suzuki¹, Chiaki Takahashi¹ (1.Cancer Res. Inst, Kanazawa Univ., 2.Sch. of Med., Keio Univ.)

BMB2015 Biochemistry and Molecular Biology |Thu. Dec 3, 2015 4:45 PM - 6:45 PM

[3P1086(4T18L-09)] Role of RB in central carbon metabolism

〇Susumu Kohno¹, Nobuyuki Okahashi², Shunsuke Kitajima¹, Sawako Suzuki³, Tomoaki Tanaka³, Fumio Matsuda², Hiroshi Shimizu², Chiaki Takahashi¹ (1.Div. Oncol. Mol. Biol., Cancer Res. Inst., Kanazawa Univ., 2.Dept. Bioinfo. Eng., Grad. Sch. IST, Osaka Univ., 3. Dept. Clin. Cell Biology, Grad. Sch. of Med., Chiba Univ.)

BMB2015 Biochemistry and Molecular Biology |Thu. Dec 3, 2015 4:45 PM - 6:45 PM

[3P1087(4T18L-10)] Anti-tumor mechanism for a G-quadruplex ligand on glioma stem cells

〇Daiki Hasegawa^1,2, Sachiko Okabe¹, Ichiro Nakano³, Kazuo Shinya⁴, Hiroyuki Seimiya^1,2 (1.Div. Mol. Biother., Cancer Chemother. Ctr., JFCR, 2.Grad. Sch. Frontier Sci., Univ. Tokyo, 3.Ohio State Univ., USA, 4.AIST)

BMB2015 Biochemistry and Molecular Biology |Thu. Dec 3, 2015 4:45 PM - 6:45 PM

[3P1088(4T18L-11)] Innovative therapeutic strategy for aggressive MYCN-amplified neuroblastoma using PI polyamide-drug conjugate

〇Hiroyuki Yoda^1,2, Atsushi Takatori¹, Takahiro Inoue^1,2, Takayoshi Watanabe¹, Nobuko Koshikawa¹, Toshinori Ozaki³, Hiroki Nagase¹ (1.Div. Cancer Genet., Chiba Cancer Ctr. Res. Inst., 2.Dep. Mol. Biol. & Oncol., Grad. Sch. Med. & Pharm. Sci., Chiba Univ., 3.Div. DNA Damage Signaling, Chiba Cancer Ctr. Res. Inst.)

BMB2015 Biochemistry and Molecular Biology |Thu. Dec 3, 2015 4:45 PM - 6:45 PM

[3P1089(4T18L-12)] Molecular design of highly selective peptide inhibitors against MMP-14

〇Yuta Sasaki¹, Shouichi Higashi¹ (1.Grad. Sch. Nanobiosci., Yokohama city Univ.)

BMB2015 Biochemistry and Molecular Biology |Thu. Dec 3, 2015 4:45 PM - 6:45 PM

[3P1090(4T18L-13)] Anticancer activities of DNA-alkylating Pyrrole-Imidazole polyamide conjugate targeting mutant KRAS

〇Kiriko Hiraoka¹, Takahiro Inoue¹, Hiroyuki Yoda¹, Sakthisri Krishnamurthy¹, Jason Lin¹, Takayoshi Watanabe¹, Atsushi Takatori¹, Nobuko Koshikawa¹, Toshikazu Bando³, Hiroshi Sugiyama³, Toshinori Ozaki², Hiroki Nagase¹ (1.Lab. Cancer Genetics, Chiba Cancer Centr. Res. Inst., 2.Lab. DNA Damage Signaling, Chiba Cancer Centr. Res. Inst., 3.Dep. Chem., Grad. Sch. Sci., Univ. Kyoto)

BMB2015 Biochemistry and Molecular Biology |Thu. Dec 3, 2015 4:45 PM - 6:45 PM

[3P1091(4T18p-01)] Elucidation of molecular mechanism by which VEGF inhibitor promote malignant phenotype of colon cancer cells

〇Chisato Tomida¹, Naoko Yamagishi², Kana Aibara¹, Chiaki Yano¹, Tomoki Abe¹, Ayako Maita¹, Takeshi Nikawa¹, Shigetada Kondo¹ (1.Inst. of Biol. Sci., Grad. Sch., Univ. of Tokushima, 2.NARO)

BMB2015 Biochemistry and Molecular Biology |Thu. Dec 3, 2015 4:45 PM - 6:45 PM