[2P0488] Targeting glycerol kinase for rational drug discovery against African trypanosomiasis

〇Emmanuel O. Balogun¹, Daniel K Inaoka¹, Tomoo Shiba², Yasutoshi Kido¹, Takeshi Nara³, Takashi Aoki³, Teruki Honma⁴, Akiko Tanaka⁴, Masayuki Inoue⁵, Shigeru Matsuoka⁵, Paul A.M. Michels⁶, Shigeharu Harada², Kiyoshi Kita¹ (1.Dept. of Biomed. Chem., Grad. Sch. of Med., Univ. of Tokyo, 2.Dept. of Appl. Biol., Grad. Sch. of Sci and Tech., Kyoto Inst. of Tech., 3.Juntendo Univ. Sch. of Med., 4.System and Struct. Biol. Center, RIKEN, 5.Grad. Sch. of Pharm. Sci., The Univ. of Tokyo, 6.Sch. of Biol. Sci., Univ. of Edinburgh, Scotland, UK.)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P0489] Molecular mechanism of bacteriolysis induced by Bac41 of opportunistic bacterial pathogen, Enterococcus faecalis.

〇Jun Kurushima¹, Haruyoshi Tomita^1,2 (1.Dept. of Bacteriol., Grad. Sch. of Med., Gunma Univ, 2.Lab. of Bacterial Drug Resistance., Grad. Sch. of Med., Gunma Univ)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P0490] Mechanisms of the regulation of ACC oxidases by nucleoside triphosphate

〇Hiroki Iio¹, Takuma Maekawa¹, Tomohide Uno¹, Kengo Kanamaru¹, Hiroshi Yamagata¹ (1.Grad. School Agric. Kobe Univ.,)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P0491] Expression and localization of diacylglycerol kinase δ in the developing mouse brain and phenotype of its brain-specific knockout mice

〇Takako Usuki¹, Tamae Takato¹, Hiromichi Sakai¹, Fumio Sakane¹ (1.Dpt. of Chem., Grad. Sch. of Sci., Univ. of Chiba)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P0492] Analysis of the Interactions between Acyl-CoA Dehydrogenase and its Substrate Analogs

〇Haruhiko Tamaoki¹, Kyosuke Sato², Takeyuki Tanaka³, Ikuko Miyahara⁴ (1.Dept. of Mol. Enzymol., Faclt. of Life Sci., Kumamoto Univ., 2.Dept. of Mol. Physiol., Faclt. of Life Sci., Kumamoto Univ., 3.Integrated Center of Sci., Ehime Univ., 4.Dept. of Chem., Grad. Sch. of Sci., Osaka City Univ.)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P0493] Crystal structure and reaction mechanism of a chitinolytic enzyme, ChiL, from Chitiniphilus shinanonensis SAY3

〇Miruku Ueda¹, Makoto Shimosaka¹, Ryoichi Arai¹ (1.Div. of Appl. Biol., Fac. of Tex. Sci. Tech., Shinshu Univ.)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P0494] Development of new drugs against fumarate respiration of Echinococcus multilocularis larval stage

〇Shigehiro Enkai¹, Daniel K Inaoka¹, Junko Ohmori¹, Kimitoshi Sakamoto², Takao Irie³, Hirokazu Kouguchi³, Kinpei Yagi³, Hiroyuki Saimoto⁴, Kiyoshi Kita¹ (1.Dept. Biomed. Chem., Grad. Sch. Med., The University of Tokyo, 2.Faculty of Agricul. Life Sci., Hirosaki Univ., 3.Dep. of Infect. Dis., Hokkaido Inst. of Pub. Health, 4.Dept. Materials Sci., Grad. Sch. Eng., Tottori Univ.)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P0495] Identification of selenium delivery system for selenophosphate synthetase in bacteria

〇Atsuki Shimizu¹, Satoru Hagita¹, Ryuta Tobe¹, Takashi Tamura², Hisaaki Mihara¹ (1.Coll. of Life Sci., Ritsumeikan Univ., 2.Grad. Sch. of Nat. Sci. and Tech., Okayama Univ.)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P0496] Studies on a new scaffold possessing inhibitory and stimulative activities against mushroom tyrosinase

〇Takahiro Oyama¹, Satoshi Takahashi², Atsushi Yoshimori², Akira Sato³, Yuka Shimizu¹, Hideaki Abe¹, Takanori Kamiya¹, Takehiko Abe¹, Sei-chi Tanuma^3,4 (1.Hinoki Shinyaku Co., Ltd., 2.Inst. for Theoretical Med., Inc., 3.Dept. of Biochem., Fac. of Pharm. Sci., Tokyo Univ. of Sci., 4.Genome & Drug Res. Ctr., Tokyo Univ. of Sci.)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM

[2P0497] Reaction Mechanism of D-Glucose Dehydrogenase from A. oryzae

〇Yuki Anase¹, Yoshitaka Nakajima¹, Yoshiaki Nishiya¹, Hiroshi Kawaminami², Masao Kitabayashi², Tadashi Yoshimoto¹, Kiyoshi Ito³ (1.Fac. Sci. Eng., Setsunan Univ., 2.TOYOBO, Tsuruga Inst., 3.Fac. Pharm Sci., Setsunan Univ.)

BMB2015 Biochemistry and Molecular Biology |Wed. Dec 2, 2015 4:45 PM - 6:45 PM