[1T15e-10(P-958)] Evaluation of the antitumor activity of the novel anti-EpCAM monoclonal antibody (EpMab-16) in colorectal adenocarcinoma

Hideki Hosono¹, Tomokazu Ohishi², ^○Teizo Asano¹, Mika K. Kaneko¹, Manabu Kawada², Yukinari Kato^1,3 (1.Dept. Antibody Drug Development, Tohoku University Grad. Sch. of Med., 2.Inst. of Microbial Chemistry (BIKAKEN), Numazu, Microbial Chemistry Res. Foundation, 3.Dept. Molecular Pharmacology, Tohoku University Grad. Sch. of Med.)

The 94th Annual Meeting of JBS |Wed. Nov 3, 2021 6:30 PM - 6:40 PM

[1T15e-11(P-962)] Mechanism of tumor selective response to STA551, a unique anti-CD137 agonist antibody activated by extracellular ATP

^○Haruka Kuroi¹, Yuji Hori¹, Meiri Kawazoe¹, Yoshinori Narita², Mika Sakurai¹, Ryo Uchikawa¹, Kenji Taniguchi¹ (1.Chugai Pharmaceutical Co., Ltd., 2.Chugai Pharmabody Research Pte. Ltd.)

The 94th Annual Meeting of JBS |Wed. Nov 3, 2021 6:40 PM - 6:50 PM

[1T15e-12(P-965)] Production of native structure-specific monoclonal antibodies against GPCRs

^○Yushi Isozaki, Kanta Tsumoto, Masahiro Tomita (Laboratory of Molecular Biotechnology, Division of Chemistry for Materials, Graduate School of Engineering, Mie University.)

The 94th Annual Meeting of JBS |Wed. Nov 3, 2021 6:50 PM - 7:00 PM

[2T13m-01(P-063)] Identification of an enzyme that synthesizes CDP-glycerol for eukaryotic glycerol phosphate modification

^○Fumiko Umezawa^1,2, Hirokazu Yagi¹, Fumiya Yamasaki³, Chu-Wei Kuo⁴, Kay-Hooi Khoo⁴, Takaya Shimura⁵, Kazuki Nakajima⁶, Hiroto Kawashima³, Koichi Kato^1,2 (1.Grad. Sch. Phar. Sci., Nagoya City Univ., 2.ExCELLS, NINS, 3.Grad. Sch. Phar. Sci., Chiba Univ., 4.Academia Sinica, 5.Grad. Sch. Med. Sci., Nagoya City Univ., 6.Center for Joint Research Facilities Support, Fujita Health Univ.)

The 94th Annual Meeting of JBS |Thu. Nov 4, 2021 9:00 AM - 9:10 AM

[2T13m-02(P-054)] Involvement of FUT8 stem region in oligomer formation and protein stability

^○Seita Tomida¹, Tetsuya Hirata², Yasuhiko Kizuka^1,2 (1.Graduates School of Natural Science and Technology, Gifu University, 2.Institute for Glyco-core Research (iGCORE), Gifu University)

The 94th Annual Meeting of JBS |Thu. Nov 4, 2021 9:10 AM - 9:20 AM

[2T13m-03(P-064)] Recognition of glycoprotein substrates by GnT-V via its specific non-catalytic luminal domain

^○Reina F. Osuka¹, Tetsuya Hirata², Masamichi Nagae³, Yasuhiko Kizuka^1,2 (1.Graduate School of Natural Science and Technology, Gifu University, 2.Institute for Glyco-core Research (iGCORE), Gifu University, 3.Department of Molecular Immunology, Research Institute for Microbial Diseases, Osaka University, Laboratory of Molecular Immunology, Immunology Frontier Research Center (IFReC), Osaka University)

The 94th Annual Meeting of JBS |Thu. Nov 4, 2021 9:20 AM - 9:30 AM

[2T13m-04(P-066)] Involvement of transcriptional factor MZF1 in transcription of human β4-galactosyltransferase 6 gene

^○Daichi Takahashi, Tatsuya Maruyama, Saori Kawaguchi, Takeshi Sato (Lab. of Glycobiol., Nagaoka Univ. of Technol.)

The 94th Annual Meeting of JBS |Thu. Nov 4, 2021 9:30 AM - 9:40 AM

[2T13m-05(P-079)] A role of NGLY1 on triple negative breast cancer

^○Haruhiko Fujihira^1,2, Yoshiya Horimoto³, Tadashi Suzuki¹ (1.Glycometabolic Biochemistry Laboratory, Cluster for Pioneering Research, RIKEN, 2.Division of Glycobiologics, Intractable Disease Research Center, Juntendo University Graduate School of Medicine, 3.Department of Breast Oncology, Juntendo University School of Medicine)

The 94th Annual Meeting of JBS |Thu. Nov 4, 2021 9:40 AM - 9:50 AM

[2T13m-06(P-070)] The activation of EGFR signaling by sialidase NEU3 and its physiological significance in human lung cancer.

^○Koji Yamamoto¹, Kohta Takahashi², Kazuhiro Shiozaki³, Kazunori Yamaguchi⁴, Hiroshi Shima⁵, Taeko Miyagi⁵ (1.Saitama Med. Univ. Faculty of Health and Med. Care., 2.Lab. Microbiol and Immunol. Pharm Sciences, Chiba Univ., 3.Faculty Fisheries, Kagoshima Univ., 4.Div. Cancer Mol. Cell. Oncol, Miyagi Cancer Ctr. Res. Inst., 5.Div. Cancer Chemother, Miyagi Cancer Ctr. Res. Inst.)

The 94th Annual Meeting of JBS |Thu. Nov 4, 2021 9:50 AM - 10:00 AM

[2T13m-07(P-073)] Biological significance of the polysialyltransferase ST8Sia2 in medaka, Oryzias latipes

^○Poh Ling Tan^1,2, Di Wu^1,2,3, Masaya Hane^1,2, Ken Kitajima^1,2,3, Chihiro Sato^1,2,3 (1.Biosci. Biotech. Center, Nagoya Univ, 2.Grad. Sch. Bioagr. Sci., Nagoya Univ., 3.iGCORE, Nagoya Univ)

The 94th Annual Meeting of JBS |Thu. Nov 4, 2021 10:00 AM - 10:10 AM