[1P-474] A role of itaconate for cancer cell growth

^〇Ayaka Saeki¹, Yoshikazu Hayashi^1,2,3, Syohei Yoshimoto^3,4, Yuji Hatakeyama ², Masato Hirata³, Eijiro Jimi¹, Tomoyo Kawakubo-Yasukochi¹ (1.OBT Research Center, faculty of Dental Science, Kyushu University, 2.Division of Functional Structure, Department of Morphological Biology, Fukuoka Dental College, 3.Oral Medicine Research Center, Fukuoka Dental College, 4.Division of Patholigical Structure, Department of Morphological Biology, Fukuoka Dental College)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-475(1T14a-01)] Downregulation of transcription factor OASIS that induces p21 expression is involved in glioblastoma development

^〇Atsushi Saito¹, Yasunao Kamikawa¹, Taichi Ito¹, Kazunori Imaizumi¹ (Department of Biochemistry, Institute of Biomedical & Health Sciences, Hiroshima University)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-476(1T14a-02)] Determining novel therapeutic targets in pancreatic cancer through comprehensive, whole-body genetic screening

^〇Masahiro Sonoshita¹ (Institute for Genetic Medicine, Hokkaido University)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-477] Relationship between acquiring 5-fluorouracil resistance and aldo-keto reductases in gastrointestinal cancer cells

Toshihiro Matsumura¹, Eriko Kashiwagi², Aki Hisamatsu³, Kazuhiro Iguchi⁴, Satoshi Endo², Kenjiro Tatematsu¹, Akira Ikari², ^〇Toshiyuki Matsunaga^1,3 (1.Laboratory of Bioinformatics, Gifu Pharmaceutical University, 2.Laboratory of Biochemistry, Gifu Pharmaceutical University, 3.Education Center of Green Pharmaceutical Sciences, Gifu Pharmaceutical University, 4.Laboratory of Community Pharmacy, Gifu Pharmaceutical University)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-478] Contribution of Regnase-1 to the malignancy of NRF2-activated non-small cell lung cancer

^〇Keito Okazaki¹, Hiroki Sekine¹, Osamu Takeuchi², Hozumi Motohashi¹ (1.Tohoku Univ., IDAC, Dept. Gene Exp. Reg., 2.Kyoto Univ. Grad. Sch. Med. Dept. Med. Biochem.)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-479] Tumor suppressive role of a NEDD8-conjugating enzyme in myeloid disease

^〇Takeshi Ueda¹, Suman Dash¹, Masahiko Honda¹, Akiyoshi Komuro¹, Hitoshi Okada¹ (Department of Biochemistry, Kindai University Faculty of Medicine, Japan)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-480] New Drug Deluvery System using Multifunctional Liposome for Oral Cancer

^〇Haruka Yamaguchi-Takezawa¹, Takamasa Suzuki², Takao Morita¹ (1.Department of Biochemistry, School of Life Dentistry at Niigata, Nippon Dental University, 2.Department of Engineering, Niigata University)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-481] DDX5 enhances E2F1 activity to activate tumor suppressor genes and contributes to E2F1-induced cell death depending on p53 in normal cells.

^〇Rinka Nakajima¹, Mashiro Shirasawa¹, Yaxuan Zhou¹, Tomoko Warita¹, Kiyoshi Ohtani¹ (Dept. of Biomed. Chem., Grad. Sch. of Sci and Tech., Kwansei Gakuin Univ.)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-482] Comprehensive tumour-associated metabolites in pancreatic cancer tissue using surgically resected specimens.

^〇Hironori F. Fukuoka¹, Hirotaka O. Ohya¹, Susumu D. Daibo¹, Tomohiro A. Andou², Takeo M. Moriya², Koji N. Narita³, Kazuya N. Nakagawa¹, Mayumi O. Ozawa¹, Atsushi I. Ishibe¹, Itaru E. Endo¹ (1.Yokohama City University, Department of Gastroenterological Surgery, 2.Axcelead Drug Discovery Partners Inc., 3.Chitose Laboratory Corp.)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-483] Effect on the novel retinoid compound for vemurafenib-resistant melanoma.

^〇Yui Suzuki¹, Souichiro Usuki², Yoshitomo Suhara¹, Ichirou Yajima¹ (1.Systems Engineering and Science, Shibaura Institute of Technology Graduate School of Engineering and Science, 2.Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University)

The 96th Annual Meeting of the Japanese Biochemical Society