[1T17a-08(1P-598)] Analysis of intracellular signaling regulation mechanism via sulfated glycolipid sulfatide in influenza A virus infection.

^〇Yoshiki Wakabayashi¹, yuuki kurebayashi¹, mizuki hayashi¹, bunta tsukamoto¹, akira minami¹, tadanobu takahashi¹, Takashi Suzuki¹, Hideyuki Takauchi¹ (University of Shizuoka)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 2:43 PM - 2:52 PM

[1T17a-09(1P-618)] Ago2 and a miRNA reduce DNA topoisomerase 1 (Top1) for enhancing DNA cleavage in antibody diversification by activation-induced cytidine deaminase (AID)

^〇Maki Kobayashi¹, Hiroyuki Wakaguri², Masakazu Shimizu², Koichiro Higasa², Fumihiko Matsuda², Tasuku Honjo¹ (1.Immunology and Genomic Medicine, Center for Cancer Immunotherapy and Immunobiology, Kyoto University Graduate School of Medicine, 2.Center for Genomic Medicine, Kyoto University Graduate School of Medicine)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 2:52 PM - 3:01 PM

[1T17a-10(1P-603)] The roles of nuclear receptor NR4A3 in inflammatory bowel disease.

^〇Natsuki Minamikawa¹, Naoto Ito¹, Mayuka Katagiri¹, Kazuki Nagata¹, Akihiko Yoshimura², Chiharu Nishiyama¹ (1.Department of Biological Science and Technology, Faculty of Advanced Engineering, Tokyo University of Science., 2.Department of Microbiology and Immunology, Keio University School of Medicine.)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 3:01 PM - 3:10 PM

[1T17a-11(2P-609)] Functional analysis of deubiquitinating enzymes that regulate IFN production signaling through the viral RNA receptor MDA5

^〇Shion Sakaguchi¹, Hirotaka Takahashi¹, Daisuke Oikawa², Fuminori Tokunaga², Kohei Nishino³, Hidetaka Kosako³, Tatsuya Sawasaki¹ (1.PROS, Ehime Univ., 2.Dept. of Med. Biochem., Grad. Sch. of Med., Osaka Metropol. Univ., 3.Fujii Memorial Institute of Med. Sci., Tokushima Univ.)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 3:10 PM - 3:19 PM

[1T17a-12(1P-614)] IkappaBzeta controls IL-17-mediated gene expression program in intestinal epithelial cells that limits expansion of SFB and prevents Th17-associated pathologies

^〇Soh Yamazaki¹, Naohiro Inohara², Masaki Ohmuraya³, Yousuke Tsuneoka⁴, Hideo Yagita⁵, Takaharu Katagiri¹, Takashi Nishina¹, Tetuo Mikami⁶, Hiroyasu Nakano¹ (1.Department of Biochemistry, Toho University School of Medicine, 2.Department of Pathology, University of Michigan Medical School, 3.Department of Genetics, Hyogo College of Medicine, 4.Department of Anatomy, Toho University School of Medicine, 5.Department of Immunology, Juntendo University Graduate School of Medicine, 6.Department of Pathology, Toho University School of Medicine)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 3:19 PM - 3:30 PM

[1T18a-01(2P-601)] Sulfur Metabolic Response in Macrophage Limits Excessive Inflammatory Response by Creating a Negative Feedback Loop

^〇Haruna Takeda¹, Shohei Murakami¹, Tomohiro Sawa², Masatomo Takahashi³, Yoshihiro Izumi³, Takeshi Bamba³, Hideyo Sato⁴, Takaaki Akaike⁵, Hiroki Sekine¹, Hozumi Motohashi¹ (1.Department of Gene Expression Regulation, Institute of Development, Aging and Cancer, Tohoku University, 2.Department of Microbiology, Graduate School of Medical Sciences, Kumamoto University, 3.Division of Metabolomics/Mass Spectrometry Center, Medical Research Center for High Depth Omics, Medical Institute of Bioregulation, Kyushu University, 4.Department of Medical Technology, Faculty of Medicine, Niigata University, 5.Department of Environmental Medicine and Molecular Toxicology, Tohoku University Graduate School of Medicine)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 1:40 PM - 1:49 PM

[1T18a-02(1P-638)] Development of a novel cell surface labeling method "CS-PeARL" and its application to protein conformational analysis

^〇Ayuka Deguchi¹, Akira Nagabukuro¹, Koji Sakai², Yuki Nishikawa², Tamami Uejima¹, Masaki Tanaka¹, Takashi Hayashi¹ (1.Department of Lead Discovery Research, Otsuka Pharmaceutical Co., Ltd., 2.Department of Medicinal Chemistry, Otsuka Pharmaceutical Co., Ltd.)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 1:49 PM - 1:58 PM

[1T18a-03(2P-628)] A small molecule enhancer of the targeted protein degradation

^〇Yuki Mori^1,2, Fumiaki Ohtake^1,2 (1.Institute for Advanced Life Science, Hoshi University, 2.Graduate school of Pharmaceutical Science, Hoshi University)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 1:58 PM - 2:07 PM

[1T18a-04(1P-636)] Binding properties of the temperature-responsive elastin-like peptide (FPGVG)₅ analog to aromatic compounds present in the environment

^〇Keitaro Suyama¹, Masayuki Murashima², Iori Maeda³, Takeru Nose^1,2 (1.Faculty of Arts and Science, Kyushu University, 2.Department of Chemistry, Faculty and Graduate School of Science, Kyushu University, 3.Department of Physics and Information Technology, Kyushu Institute of Technology)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 2:07 PM - 2:16 PM

[1T18a-05(1P-630)] Identification of SREBP-1 binders by high-throughput screening

^〇Kahori Hiro¹, Yu Takahashi¹, Takashi Maruyama¹, Takayoshi Okabe², Hirotatsu Kojima², Yoshio Yamauchi¹, Ryuichiro Sato¹ (1.Graduate School of Agricultural and Life Sciences, The University of Tokyo, 2.Graduate School of Pharmaceutical Sciences, The University of Tokyo)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 2:16 PM - 2:25 PM