[1T15a-12(1P-627)] Differential toxicity and localization of arginine-rich C9ORF72 dipeptide repeat proteins depend on de-clustering of positive charges.

^〇Tamami Miyagi¹, Rio Yamazaki¹, Kohsuke Kanekura¹ (Dept. pharmacology, Tokyo medical university)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 3:19 PM - 3:30 PM

[1T16a-01(2P-632)] Establishment of GFP Tagged Tau based High Content Screening for the Tau Modifiers Discovery

^〇Maika Itsuno¹, Sumihiro Maeda¹, Hideyuki Okano¹ (Keio University School of Medicine)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 1:40 PM - 1:49 PM

[1T16a-02(2P-562)] Molecular mechanisms of synaptic competition for developmental dendrite pruning

^〇Satoshi Fujimoto¹, Marcus N. Leiwe¹, Shuhei Aihara¹, Richi Sakaguchi¹, Yuko Muroyama², Reiko Kobayakawa³, Ko Kobayakawa³, Tetsuichiro Saito², Takeshi Imai¹ (1. Graduate School of Medical Sciences, Kyushu University, 2.Graduate School of Medicine, Chiba University, 3.Institute of Biomedical Science, Kansai Medical University)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 1:49 PM - 1:58 PM

[1T16a-03(2P-561)] Functional analysis of Ankyrin-repeat proteins Panky and Panky-like in the mouse retina

^〇Daichi Gyoten¹, Hung-Ya Tu¹, Hitoshi Sumihiro¹, Kayoko Michikawa¹, Kazuki Fujieda¹, Naoko Kajimura², Taro Chaya¹, Takahisa Furukawa¹ (1.Laboratory for Molecular and Developmental Biology, Institute for Protein Research, Osaka University, AMED-CREST, JST MS, JST COI-NEXT, 2.Research Center for Ultra-High Voltage Electron Microscopy, Osaka University)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 1:58 PM - 2:07 PM

[1T16a-04(1P-552)] The effect of prenatal anesthetic exposure on neural stem cell behavior and its mechanism

^〇Kosuke Nakashima^1,2, Taito Matsuda¹, Hiroyoshi Doi², Ken Yamaura², Kinichi Nakashima¹ (1.Stem Cell Biology and Medicine, Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, 2.Department of Anesthesiology and Critical Care Medicine, Graduate School of Medical Sciences, Kyushu University)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 2:07 PM - 2:16 PM

[1T16a-05(1P-554)] Analysis of Gα signaling in vagal afferent neuron using DREADD system

^〇Masaki Nakamura¹, Kuniyuki Kano¹, Asuka Inoue², Junken Aoki¹ (1.Grad. Sch. Of Pherm. Sci., Tokyo Univ., 2.Grad. Sch. Of Pherm. Sci., Tohoku Univ.)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 2:16 PM - 2:25 PM

[1T16a-06(1P-558)] Anaplastic lymphoma kinase regulates body weight by suppressing sympathetic neuron

^〇Yuji Suzuki¹, Kazuma Sakamoto^1,2, Kenji Kadomatsu² (1.Department of Molecular Biology, Graduate School of Medicine, Nagoya University, 2.Institute of Glyco-core Research)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 2:25 PM - 2:34 PM

[1T16a-07(1P-561)] Identification of salt-inducible kinase 3 as a novel tau kinase using a Drosophila model expressing human tau in noradrenaline/octopamine neurons

^〇Sachie Chikamatsu^1,2, Risa Nishijima², Kimi Takei², Kazuhiko Kume³, Koichi M. Iijima^1,2, Michiko Sekiya^1,2 (1.Department of Experimental Gerontology, Graduate School of Pharmaceutical Sciences, Nagoya City University, 2.Department of Neurogenetics, National Center for Geriatrics and Gerontology, 3.Department of Neuropharmacology, Graduate School of Pharmaceutical Sciences, Nagoya City University)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 2:34 PM - 2:43 PM

[1T16a-08(2P-575)] Analysis of the regulatory mechanism of striatal dopamine release in mice by a dyskinesia-associated molecule, proline-rich transmembrane protein 2 (PRRT2)

^〇Shiho Makiya¹, Kaito Kanamoto¹, Daisuke Hatta¹, Tatsuya Kishino², Yuki Fuchigami³, Shigeru Kawakami³, Akira Kinoshita⁴, Koh-ichiro Yoshiura⁴, Naohiro Kurotaki⁴, Keiro Shirotani¹, Nobuhisa Iwata¹ (1.Department of Genome-based Drug Discovery, Graduate School of Biomedical Sciences, Nagasaki University., 2.Division of Functional Genomics, Research Center for Advanced Genomics, Nagasaki University., 3.Department of Pharmaceutical Informatics, Graduate School of Biomedical Sciences, Nagasaki University., 4.Department of Human Genetics, Atomic Bomb Disease Institute, Graduate School of Biomedical Sciences, Nagasaki University.)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 2:43 PM - 2:52 PM

[1T16a-09(2P-567)] Hyperpolarization of mitochondria underlies neurodegeneration in a fly model of tau toxicity

^〇Arisa Tamura¹, Marie Noguchi¹, Naoko Nozawa¹, Akiko Asada¹, Taro Saito¹, Kanae Ando¹ (Department of Biological Sciences, Graduate School of Science, Tokyo Metropolitan University)

The 96th Annual Meeting of the Japanese Biochemical Society |Tue. Oct 31, 2023 2:52 PM - 3:01 PM