The Japanese Biochemical Society

[2P-187] Mechanism of action of an antimalarial compound isolated from Nagasaki University's marine microbial extracts: targeting mitochondrial electron transport chain

Normalita Eka Pravitasari1,2, Takaya Sakura1,3, Kibet Ng'etich Japheth4,5, Jun Takouda6, Shusaku Mizukami7, Kenji Hirayama1,8, Kohsuke Takeda6, Yoshimasa Tanaka9, Kiyoshi Kita1,10,11, Daniel Ken Inaoka1,3,11 (1.School of Tropical Medicine and Global Health, Nagasaki University, 2.Struct Mol and Regener Med, Eijkman Res Center for Mol Biol Nat Res and Innov, 3.Department of Molecular Infection Dynamics, Institute of Tropical Medicine (NEKKEN), Nagasaki University, 4.Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, 5.Center for Trad Med and Drug Res, Kenya Med Res Inst, 6.Department of Cell Regulation, Graduate School of Biomedical Sciences, Nagasaki University, 7.Department of Immune Regulation, Institute of Tropical Medicine (NEKKEN), Nagasaki University, 8.Department of Immunogenetics, Institute of Tropical Medicine (NEKKEN), Nagasaki University, 9.Center for Medical Innovation, Nagasaki University, 10.Department of Host-Defense Biochemistry, Institute of Tropical Medicine (NEKKEN), Nagasaki University, 11.Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-189] Dynamic Structural Analysis of NADPH-cytochrome P450 reductase by HDX-MS using MALDI-TOF MS

Syota Uemura1, Ryuta Nakamura1, Tomoichiro Kusumoto2, Junichi Taira1, Masakazu Sugishima3, Hiroshi Sakamoto1 (1.Department of Bioscience and Bioinformatics, Graduate School of Computer science and Systems Engineering, Kyushu Institute of Technology, 2.Department of Technical Support, Kyushu Institute of Technology, 3.Department of Medical Biochemistry, Kurume University School of Medicine)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-191] Schistosoma mansoni sulfide:quinone oxidoreductase forms stable charge transfer-complexes with sulfide, sulfite, L-cysteine, and cyanide

Augustin T. Kabongo1, Kiplangat Talaam K.2,3, Matsuo Yuchi1,4, Rajib Acharjee2,3, Yamashita Tetsuo5, Yazaki Euki6, Hartuti Endah D.2,3, Matsunaga Tetsuo7, Ida Tomoaki7, Nozaki Tomoyoshi8, Akaike Takaaki7, Hamano Shinjiro1,2,3, Kita Kiyoshi1,2, Inaoka Daniel K.1,2 (1.School of Tropical Medicine and Global Health, Nagasaki University, Japan, 2.Institute of Tropical Medicine (NEKKEN), Nagasaki University, Japan, 3.Program for Nurturing Global Leaders in Tropical and Emerging Communicable Disease, Graduate School of Biomedical Sciences, Nagasaki University, Japan, 4.Graduate School of Life Science, Kumamoto University, Japan, 5.Department of Cardiovascular Physiology, Faculty of Medicine, Kagawa University, Japan, 6.Interdisciplinary Theoretical and Mathematical Sciences (iTHEMS), RIKEN , Japan, 7.Department of Environmental Medicine and Molecular Toxicology, Graduate School of Medicine, Tohoku University, Japan, 8.Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, Japan)

The 96th Annual Meeting of the Japanese Biochemical Society