[1P-0592] Mono-carbonyl curcumin analogs, PGV-1: Candidate target genes involved in chemo-preventive activity against DMH-induced colorectal cancer rat model

^○Febri Wulandari¹, Muthi Ikawati^{1, 2}, Mitsunori Kirihata³, Sitarina Widyarini⁴, JunYa Kato⁵, Edy Meiyanto^{1, 2} (1.Cancer Chemoprevention Research Center, Faculty of Pharmacy, Univ. Gadjah Mada, Indonesia, 2.Macromolecular Engineering Laboratory, Dept. of Pharmaceutical Chemistry, Faculty of Pharmacy, Univ. Gadjah Mada, Indonesia, 3.Research Center of Boron Neutron Capture Therapy, Research Organization for the 21st Century, Osaka Prefecture Univ., Japan, 4.Veterinary Faculty, Univ. Gadjah Mada, Indonesia, 5.Laboratory of Tumor Cell Biology, Division of Biological Science, Graduate School of Science and Technology, Nara Institute of Sci. and Tech., Japan)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0593] Novel regulatory mechanism of GTP metabolic switch functioning as a GTP sensor

^○Natsuki Osaka¹, Hongyang YU², Toshiya Senda², Atsuo Sasaki^{1, 3} (1.Institute for Advanced Biosciences, Keio University, 2.Institute of Materials Structure Science, High Energy Accelerator Research Organization, 3.University of Cincinnati College of Medicine)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0594] The regulatory roles of branched-chain amino acid metabolites in pyruvate metabolism

^○Kiyoto Nishi^{1, 2}, Eiichiro Nishi¹, Rong Tian² (1.Dept. of Pharmacol., Shiga Univ. of Med. Sci., 2.Dept. of APM, Univ. of Washington)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0595] Induction of Basal Autophagy by FBXO22 under Stress from Nutrient Starvation

^○Narumi Suzuki¹, Yoshikazu Johmura², Makoto Nakanishi² (1.Dept. of Biol. Sci., Grad. Sch. of Sci., Univ. of Tokyo, 2.IMSUT, Univ. of Tokyo)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0596] Circadian rhythm of liver fibrosis in nonalcoholic steatohepatitis (NASH).

^○Taira Wada, Mayu Tanabe, Hirotake Ishii, Yukiko Takasugi, Shigeki Shimba (Sch. of Sci., Nihon Univ.)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0597] Upregulation of thymidylate synthase induces drug resistance in malignant pleural mesothelioma

^○Yuzo Sato^{1, 2}, Hideki Makinoshima³, Masaru Tomita² (1.Syst. Biol. Prog. Grad. Sch. Media & Governance, Keio Univ., 2.Inst. Adv. Biosci., Keio Univ., 3.NCC-EPOC)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0598] Development of a Simple Fluorescence Assay for Cystine Uptake via the Cystine transporter (xCT) using Selenocystine.

^○Norio Hirakawa, Takashi Shimomura, Yuya Ohuchi (Dojindo Laboratories)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0599] Development of an AAV-based therapeutic model for NAFLD/NASH

^○Shun Fujinuma¹, Hirokazu Nakatsumi², Keiichi Nakayama¹ (1.Dept. of Mol. and Cell. Biol., Med. Inst. of Bioreg., Kyushu Univ., 2.Dept. of Mol. Biol., Grad. Sch. of Pharm. Sci., Nagoya city Univ.)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0600] Basic analysis of carcinogenic induction mechanism by non-mutagenic carcinogenic compounds

^○Natsuko Ozawa¹, Hiromasa Imaishi^{1, 2} (1.Division of Applied Biology, Environmental Material Science, Faculty of Agriculture, Kobe University, 2.Laboratory of Response to Environmental Materials, Division of Signal Responses, Biosignal Research Center, Kobe University)

The 44th Annual Meeting of the Molecular Biology Society of Japan

[1P-0601] CRISPR/Cas9-based rescue experiment of a nonsense mutation in a type 2 diabetes mellitus candidate gene

^○Naoki Adachi¹, Tomoki Hirokoji¹, Saki Shigenaka¹, Kenta Nakano², Minako Yoshihara³, Yusaku Yoshida⁴, Shigeo Yokose⁴, Yukio Taniguchi¹, Norio Harada⁵, Nobuya Inagaki⁵, Harumi Takahashi⁶, Susumu Seino⁶, Tadashi Okamura², Mikita Suyama³, Norihide Yokoi^{1, 6} (1.Lab. of Anim. Breed. & Genet., Grad. Sch. of Agric., Kyoto Univ., 2.Dept. of Lab. Anim. Med., Res. Inst., Natl. Ctr. for Glob. Health and Med., 3.Div. of Bioinform., Med. Inst. of Bioregulation, Kyushu Univ., 4.Japan SLC, Inc., 5.Dept. of Diabet., Endocrinol. & Nutr., Grad. Sch. of Med., Kyoto Univ., 6.Div. of Molec. & Metab. Med., Grad. Sch. of Med., Kobe Univ.)

The 44th Annual Meeting of the Molecular Biology Society of Japan