[31-413-am] 天然物由来・生体由来医薬品、合成医薬品

[31-413-am04S] Enhancing T-cell activation: Synthesis of meta-carboranes regulating CD28 binding to SH2 domains of Grb2 and PI3K

○YUJIE SHAO¹, Yasunobu Asawa¹, Shuhei Ogawa², Saki Ochi³, Atsushi Yoshimori⁴, Masayuki Oda³, Hiroyuki Nakamura^1,5 (1. School of Life Science and Technology, Tokyo Institute of Technology., 2. Research Institute for Biomedical Sciences, Tokyo University of Science., 3. Graduate School of Life and Environmental Sciences, Kyoto Prefectural University., 4. Institute for Theoretical Medicine, Inc., 5. Institute of Innovative Research, Tokyo Institute of Technology)