[1P-054] Phospholipase A and acyltransferase 1 (PLAAT1) deficiency ameliorate obesity and hepatic lipid accumulation in mice

^〇Sumire Sasaki¹, S.M. Khaledur Rahman¹, Toru Uyama¹, Zahir Hussain¹, Mohammad Mamun Sikder¹, Hiroyuki Saiga², Ken-ichi Ohta³, Yoshimi Miki⁴, Hoshino Katsuaki ², Ueno Masaki ⁵, Makoto Murakami⁴, Ueda Ueda¹ (1.Department of Biochemistry, Kagawa University School of Medicine, Kagawa, Japan, 2.Department of Immunology, Kagawa University School of Medicine, Kagawa, Japan, 3.Department of Anatomy and Neurobiology, Kagawa University School of Medicine, Kagawa, Japan , 4.Laboratory of Microenvironmental and Metabolic Health Science, Center for Disease Biology and Integrative Medicine, Faculty of Medicine, The University of Tokyo, Tokyo, Japan, 5.Department of Inflammation Pathology, Kagawa University School of Medicine, Kagawa, Japan)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-055] Lysophospholipid acyltransferase LPLAT10/LPCAT4/LPEAT2 overexpression in the liver increases glucose-dependent insulin secretion

^〇Kahori Shimizu¹, Moe Ono¹, Takenari Mikamoto¹, Yuya Urayama¹, Hiroki Nakanishi², Shotaro Michinaga³, Sena Yoshida¹, Miho Iwasaki¹, Tomoyuki Terada¹, Fuminori Sakurai⁴, Hiroyuki Mizuguchi^4,5,6,7,8, Hideo Shindou^9,10, Koji Tomit¹, Toru Nishinaka¹ (1.Pharm., Osaka Ohtani Univ., 2.Lipidome Lab Co., Ltd., 3.Meiji Pharm. Univ., 4.Grad. Sch. of Pharma. Sci., Osaka Univ., 5.Natl. Inst. of Biomed. Innov. Health Nutr., 6.MEIC, Osaka Univ., 7.OTRI, Osaka Univ., 8.CiDER, Osaka Univ., 9.NCGM, 10.Univ. of Tokyo)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-056] Substrate specificity and structural basis of the final enzymes catalyzing de novo synthesis of choline/ethanolamine phospholipids

^〇Yasuhiro Horibata¹, Jacquelyn Roberts², Ohi Melanie², Shoji Maeda^3,4, Hiroyuki Sugimoto¹ (1.Dokkyo Medical University School of Medicine, 2.Life Science Institute, University of Michigan, 3.Department of Pharmacology, Medical School, University of Michigan, 4.Present address: Discovery Research, Exelixis Inc.)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-057] Plasmalogen-mediated activation of receptor potential cation channel promotes AMPK activity

^〇Masanori Honsho¹, Shiro Mawatari², Takehiko Fujino ² (1.Grad. Sch. of Med. Sci., Kyushu Univ., 2.Inst. of Rheolog. Funct. of Food)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-058(1T02a-12)] Function of long chain fatty alcohol-producing enzyme FAR1 in the nervous system

^〇Tenga Takahashi¹, Kento Otsuka¹, Takayuki Sassa^1,2, Akio Kihara^1,2 (1.Grad. Sch. Life Sci., Hokkaido Univ., 2.Fac. Pharm. Sci., Hokkaido Univ.)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-059] Search for oxidized phospholipids that characterize ferroptosis

^〇Yuka Jinnouchi¹, Hideto Naka¹, Ryoto Ito¹, Mirinthorn Jutanom¹, Kazushi Morimoto¹, Ken-ichi Yamada¹ (Faculty of Pharmaceutical Sciences, Kyushu University)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-060] Oxysterol and transcriptional factors regulating phosphatidylethanolamine and cholesterol biosynthesis

^〇Hiromi Ando¹, Yasuhiro Horibata¹, Hiroyuki Sugimoto¹ (Dep of Biochemistry, Dokkyo medical university)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-061] Chemical tools for studying lysophospholipid lipases

^〇Hyeon-Cheol Lee-Okada¹, Takero Hanada¹, Takehiko Yokomizo¹ (Juntendo University School of Medicine)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-062] The physiological role of PLCXD2 in the liver

^〇Riku Usami¹, Kaori Kanemaru², Yoshikazu Nakamura² (1.Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science, 2.Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-063] The functional analysis of PLC-like protein in the mouse retina

^〇Akira Katayanagi¹, Kaori Kanemaru², Yosikazu Nakamura² (1.Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science, 2.Department of Applied Biological Science, Faculty of Science and Technology, Tokyo University of Science)

The 96th Annual Meeting of the Japanese Biochemical Society