A novel inhibitor of succinyl CoA:3-ketoacid CoA transferase (SCOT) with reduced brain penetration maintains glucose-lowering actions in experimental obesity

○Seyed Amirhossein Tabatabaei Dakhili

[30P-pm097] A novel inhibitor of succinyl CoA:3-ketoacid CoA transferase (SCOT) with reduced brain penetration maintains glucose-lowering actions in experimental obesity

○Seyed Amirhossein Tabatabaei Dakhili¹, Kunyan Yang¹, Rabih Abou Farraj², Hamdah Al-Nebaihi¹, Christina Saed¹, Rakesh Bhat², Amanda Greenwell¹, Jordan Chan¹, Indiresh Mangra-Bala¹, Keshav Gopal¹, Tanin Shafaati¹, Farah Eaton¹, Sally Ferrari¹, Carlos Velazquez-Martinez¹, MIchael Overduin², Mark Glover², Dion Brocks¹, John Ussher¹ (1. Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada., 2. Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada.)

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Presentation information

[30P-pm] Drug design/Screening/adioisotopes, radiopharmaceuticals/Others

[30P-pm097] A novel inhibitor of succinyl CoA:3-ketoacid CoA transferase (SCOT) with reduced brain penetration maintains glucose-lowering actions in experimental obesity

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